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Anxiety: all studies

Page 313 of 769: studies 3,121 to 3,130 of 7,689, newest first. Back to the anxiety overview

Research

Ketamine Dose and Duration Effects in Internalizing Disorders

The Journal of Clinical Pharmacology September 1, 2026 Neil McNaughton, Ben Beaglehole, Paul Glue

The dose-response profile of racemic ketamine in internalizing disorders is poorly characterized. This was a secondary analysis of outcome responses in patients with treatment-resistant depression, post-traumatic stress disorder, generalized and/or social anxiety, or obsessive-compulsive disorder. For each disorder, they received single intramuscular doses of racemic ketamine (0.5 and 1.0...

551. Esketamine in neuropsychiatric long COVID: a retrospective analysis

The International Journal of Neuropsychopharmacology September 1, 2026 N Hartman, D Ivkic, M C Dorczok et al.

Neuropsychiatric manifestations of Long COVID (LC) frequently include post-exertional malaise (Cheng et al. , 2025), fatigue, cognitive dysfunction and impairment, sleep disturbances, post-traumatic stress, autonomic dysregulation, pain, inner tension, psychomotor retardation, aberrations in appetite and weight (Badenoch et al. , 2022; O'Mahoney et al. , 2025), showing substantial clinical and...

859. From Neurons to Behavior: Preclinical Insights into LSD’s Anxiolytic Mechanisms

The International Journal of Neuropsychopharmacology September 1, 2026 Gabriella Gobbi

Abstract Background Lysergic acid diethylamide (LSD), a serotonergic psychedelic, has gained renewed interest for its potential anxiolytic effects in clinical trials. However, the neurobiological mechanisms underlying these effects remain poorly understood. Aims & Objectives The goal of this study is to understand the mechanism of action of LSD in animal models by using in vivo...

Psilocybin Restores Spatial Memory but Not Fronto-Hippocampal Synchrony in a Rat Model of Alzheimer's Disease

Neuroscience Research September 1, 2026 Mersedeh Shamsedin

ABSTRACT Background Fronto-hippocampal desynchronization is linked to cognitive decline in Alzheimer's-like pathology, but whether psilocybin can restore this dysfunction is unknown. Methods Male rats received intracerebroventricular streptozotocin (ICV-STZ) to induce neurotoxicity, followed by a single dose of psilocybin (2.5 mg/kg, the maximum tolerated dose). Spatial memory, recognition...

Psilocybin, From Ancestral Use to Therapeutic Potential: A Multidimensional Review of Its Pharmacological Basis and Current Perspectives

Human Psychopharmacology: Clinical and Experimental September 1, 2026 José Norberto Vásquez-Bonilla

OBJECTIVE: This review critically examines psilocybin, with particular emphasis on its pharmacokinetics and pharmacodynamics, including its serotonergic, neuroplastic, and anti-inflammatory mechanisms. It integrates historical context, preclinical and clinical evidence, and evaluates emerging therapeutic potential, safety, microdosing practices, and pharmacological interactions. METHODS: A...

A signaling signature distinguishes hallucinogenic from non-hallucinogenic psychedelics

Translational Psychiatry September 1, 2026 Sandra M. Martin-Guerrero, Marco Taddei-Tardón, Jessica L Maltman et al.

Abstract Psychedelic drugs can induce intense changes in perception and thought, and some also promote long-lasting adaptations in brain circuits that are being explored for treatment of mood and anxiety disorders. How these compounds differ at the level of intracellular signaling, and how hallucinogenic drugs diverge from related non-hallucinogenic forms, is poorly understood. A central...

Contribution of the Serotonin 5-HT2A Receptor to the Therapeutic Effect of Psilocin on Social Behavior Deficits in Mice Repeatedly Exposed to Social Defeat Stress.

Neuropsychopharmacology Reports September 1, 2026 Daisuke Ibi, Rika Takaba, Keisuke Yoshida et al.

Psychedelics such as psilocybin and lysergic acid diethylamide (LSD) exert hallucinogenic effects through stimulation of serotonin 5-HT2A receptors (5-HT2ARs) in the cerebral cortex. In recent years, numerous reports have demonstrated that psychedelics are effective in treating various psychiatric disorders such as major depressive disorder (MDD), treatment-resistant depression (TRD), and...

The Integrated Meditative-Healing Genealogy of the Three Scriptures of Korean Sundo and Its Application to Care and Death Education

Journal of Korean Sundo Culture August 31, 2026 Moon Jeong Choi

본 연구는 한국 선도(仙道) 전통의 3대 경전인 『천부경(天符經)』, 『삼일신고(三一神誥)』, 그리고 동학(東學)의 경전을 하나의 유기적 수행 계보(genealogy of practice)로 재구성하고, 이를 현대 명상학·신경과학·소마(soma) 심리학의 언어로 해명한 뒤, 선도 경전을 돌봄(care)과 죽음교육(death education)의 이론적 자원으로 재구성·정립하는 데 목적이 있다. 즉 본 연구는 경전 분석과 실천적 적용을 별개의 주제로 병치하지 않고, ‘선도경전이 왜 돌봄·죽음교육의 수행적 자원이 되는가’라는 하나의 물음을 처음부터 관통시킨다. 서구의 마음챙김 기반 접근(MBSR/MBCT)이 한국 사회의 화병(火病)과 같은 문화 특수적 정서 문제와 관계적·사회적 치유의 차원을 충분히...

Reconfiguring Tradition: Baul Performance and the Politics of Folk Authenticity

The Criterion An International Journal in English August 31, 2026 Sukhiram Kumar, Amar Nath Kumar

Bengal has a glorious and long-standing lineage of folk traditions.Amongst them, Baul tradition stands at the acme of the indigenous hierarchy of Bengal (both East and West Bengal).Baul tradition is exclusively an amalgamation of various distinctive religious traditions including Sufi mysticism, Sahajiya Buddhism, and Tantric philosophies.Baul practices historically resisted the established...

“Healing the Healer: A Case Report of Recovery from Severe Depression in an Experienced Yoga Prana Vidya (YPV) Practitioner”

International Journal of Medical Science and Clinical Research Studies August 31, 2026 Kumkum Saxena, C Shalini

Depression is a major mental health disorder influenced by biological, psychological, and social factors. Family conflict, lack of social support, and loss of purpose can increase vulnerability to depression. Yoga Prana Vidya (YPV) is an integrated complementary healthcare system that combines rhythmic breathing, meditation, physical exercises, forgiveness practices, no-touch energy healing,...