Behavioral Sciences
August 31, 2021
Sherry-Anne Muscat, Geralyn Dorothy Wright, Kristy Bergeron et al.
5 citations
Ketamine therapy with culturally attuned trauma-informed psychotherapy in a collaborative cross-cultural partnership may provide a critical step in the operationalization and optimization of treatment effectiveness in diverse populations and may provide a foundation for an improved quality of life for Indigenous people. Decolonizing Indigenous health and wellbeing is long overdue, requiring an...
Journal of Psychedelic Studies
August 26, 2021
Kim van Oorsouw, Malin V. Uthaug, Natasha L. Mason et al.
16 citations
Abstract Background and aims There is a growing body of evidence suggesting that the psychedelic plant tea, ayahuasca, holds therapeutic potential. Uthaug et al. (2018) demonstrated that a single dose of ayahuasca improved mental health sub-acutely and 4-weeks post-ceremony in healthy participants. The present study aimed to replicate and extend these findings. A first objective was to assess...
Frontiers in Psychology
August 19, 2021
Jessica Sophie Corneille, David Luke
61 citations
Spontaneous Spiritual Awakenings (SSAs) are subjective experiences characterised by a sudden sense of direct contact, union, or complete nondual merging (experience of oneness) with a perceived ultimate reality, the universe, “God,” or the divine. These profound transformative experiences have scarcely been researched, despite extensive anecdotal evidence suggesting their potential to catalyse...
Frontiers in Neuroscience
August 11, 2021
Pieter J. Vis, Anneke E. Goudriaan, Bastiaan C. Ter Meulen et al.
40 citations
Hallucinogen-persisting perception disorder (HPPD) features as a diagnostic category in the DSM-5, ICD-11, and other major classifications, but our knowledge of the phenomenology of the perceptual symptoms involved and the changes in consciousness during the characteristic “flashbacks” is limited. We systematically evaluated original case reports and case series on HPPD to define its...
Current Opinion in Anaesthesiology
August 1, 2021
Sabine Himmelseher, Eberhard F Kochs
To update pharmacological insights on ketamine integrating information from different disciplines for developing steps to "breakthrough" approaches in clinical challenges. Pharmacokinetic/pharmacodynamic (PK/PD) models have incorporated recirculation, ketamine metabolites, drug-drug interaction, and covariates such as age. Ketamine-induced relief from treatment-resistant depression has been...
Spirituality and Mental Health Across Cultures
August 1, 2021
Etzel Cardeña, Lena Lindström
Throughout history, people have described alterations of consciousness in which they experienced a sense of transcendence, being part of a much larger unity, sometimes encompassing the whole universe, or of being pure awareness. These experiences have been foundational for many religious and spiritual practices, albeit they have sometimes been treated as suspect or outright psycho- and or...
Oxford University Press eBooks
August 1, 2021
Chris Letheby
Philosophy of Psychedelics is the first scholarly monograph in English devoted to the philosophical analysis of psychedelic drugs. Its central focus is the apparent conflict between the growing use of psychedelics in psychiatry and the philosophical worldview of naturalism, which holds that the natural world is all that exists. The book reviews scientific evidence that psychedelics such as...
Journal of Psychopharmacology
August 1, 2021
Rachael Sumner, Emme Chacko, Rebecca McMillan et al.
68 citations
Ketamine is central to one of the most rapidly growing areas of neuroscientific research into novel treatments for depression. Limited research has indicated that the psychedelic properties of ketamine may play a role in its antidepressant effects. The aim of the current study was to explore the psychedelic experiences and sustained impact of ketamine in major depressive disorder. In the...
HTS Teologiese Studies / Theological Studies
July 29, 2021
R. A. Northover
3 citations
The study reappraised Emile Durkheim’s totemic principle in relation to the origins of religion and culture, using, amongst others, speech act theory and recent southern African epistemologies, especially David Lewis-Williams’ theory of shamanism, potency and altered states of consciousness. The study was text-based, qualitative and interpretive, and used key texts from anthropology,...
Proceedings of the National Academy of Sciences
July 23, 2021
Lennart R.b. Spindler, Andrea I. Luppi, Ram Adapa et al.
Significance Understanding the neural bases of consciousness is of basic scientific and clinical importance. Human neuroimaging has established that a network of interconnected brain regions known as the default mode network disintegrates in anesthesia and after brain damage that causes disorders of consciousness. However, the neurochemical underpinnings of this network change remain largely...