PLoS One
2023
Ana Paula Gonçalves Donate, Elizeu Coutinho De Macedo, Andre Bedendo et al.
This study aimed to investigate the effects of Mindfulness-Based Relapse Prevention (MBRP) in decision-making, inhibitory control and impulsivity compared to Treatment as Usual (TAU) for individuals with Substance Use Disorders (SUD's) in Brazil. A randomized clinical trial was conducted with participants from a therapeutic community (n = 122). Decision-making (Iowa Gambling Task), impulsivity...
Frontiers in Psychiatry
2023
Annika Rosenthal, Maria Garbusow, Nina Romanczuk-Seiferth et al.
Pavlovian conditioned contextual cues have been suggested to modulate instrumental action and might explain maladaptive behavior such as relapse in participants suffering from alcohol use disorder (AUD). Pavlovian-to-Instrumental transfer (PIT) experimentally assesses the magnitude of this context-dependent effect and studies have shown a larger PIT effect in AUD populations. Taken this into...
JAMA Psychiatry
2023
Brian D Kiluk, Bethea A Kleykamp, Sandra D Comer et al.
22 citations
Novel treatments for opioid use disorder (OUD) are needed to address both the ongoing opioid epidemic and long-standing barriers to existing OUD treatments that target the endogenous μ-opioid receptor (MOR) system. The goal of this review is to highlight unique clinical trial design considerations for the study of emerging treatments for OUD that address targets beyond the MOR system. In...
Biologie aujourd'hui
2023
Fahd Hilal, Jérôme Jeanblanc, Mickaël Naassïla
3 citations
Alcohol Use Disorder (AUD) is a psychiatric condition characterized by chronic and excessive drinking despite negative consequences on overall health and social or occupational functioning. There are currently limited treatment options available for AUD, and the effects size and the response rates to these treatments are often low to moderate. The World Health Organization has identified the...
Hop and Medicinal Plants
December 28, 2022
Vanessa Eveline Vlaic, Andreea Ona
The therapeutic use of the substance psilocin produced by the fungi from the genus named Psilocybe has been an interesting but also controversial topic of discussion among researchers since the 1950s until now. These fungi can synthesize several alkaloids such as psilocybin, which has hallucinogenic properties, but also muscarine, which is a toxic substance that stimulates that part of the...
Case Reports in Psychiatry
December 15, 2022
Zeeshan Faruqui, Christopher Kim
Alcohol use disorder (AUD) is especially prevalent among individuals with major depressive disorder (MDD) and is associated with higher morbidity, mortality, disability, and risk for suicide. Intranasal esketamine has been documented to be a safe and effective option for treatment resistant MDD and received US FDA approval in 2019. However, the availability of esketamine is limited due to...
Frontiers in Psychology
December 5, 2022
Chunhui You, Yang Liu
As social media has become more imperative in daily life, people pay more attention to self-presentation and impression management on social media, and some have even become psychologically dependent. There is a large group of socially addicted users who continuously strive to improve their online self-presentation. Due to stress and burnout arising from social media addiction, people change...
Journal of Addiction & Addictive Disorders
December 2, 2022
Suchismita Ray
The opioid epidemic continues to be a growing public health concern in the United States, with Black mothers who have young children being a particularly vulnerable population. In this review, the authors first summarize the mental and physical health disparities faced by this population from the perspective of minority stress theory, considering the role of racial discrimination, gender...
Contemporary Clinical Trials
December 1, 2022
Kelley C O'Donnell, Sarah E. Mennenga, Lindsey T. Owens et al.
24 citations
Several lines of evidence suggest that classic psychedelics (5-HT2A receptor agonists or partial agonists) such as psilocybin might facilitate behavior change in individuals with substance use disorders. We conducted a multi-site, double-blind, randomized controlled trial (RCT) to assess the effects of psilocybin-assisted psychotherapy in alcohol-dependent volunteers. In addition to a...
OBM Integrative and Complementary Medicine
November 14, 2022
Nils Altner, Jasmin Friedrich
3 citations
In this study, we present the results of a 48-hour mindfulness-based and compassion-based training for teachers (N = 59). This study included 3,250 students in two years. We strengthened the resources of teachers and students for health, especially for preventing addiction. The didactic approach was based on the concepts of embodiment and resonance. We first trained teachers and then encouraged...