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A randomised controlled trial of stress reduction for hypertension in older African Americans.

Robert H Schneider, Frank Staggers, C N Alxander, William Sheppard, M Rainforth, K Kondwani, S Smith, C G King

Hypertension November 1, 1995 DOI: 10.1161/01.hyp.26.5.820 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Randomized controlled single-blind trial Peer reviewed
Sample size 127
Population African American men and women aged 55 to 85 years with mild hypertension (initial diastolic pressure 90 to 109 mm Hg, systolic pressure <=189 mm Hg, final baseline blood pressure <=179/104 mm Hg) at an inner-city primary care health center
Interventions Transcendental Meditation progressive muscle relaxation lifestyle modification education control program
Duration 3 months of follow-up
Topics Meditation
Keywords Humans Hypertension Follow-up studies Single-blind method Stress, psychological Patient compliance Middle aged Female Black people
Key findings Compared with a lifestyle modification education control, Transcendental Meditation reduced systolic pressure by 10.7 mm Hg and diastolic pressure by 6.4 mm Hg, while progressive muscle relaxation lowered systolic pressure by 4.7 mm Hg and diastolic pressure by 3.3 mm Hg. The meditation group's reductions were significantly greater than the relaxation group's for both systolic and diastolic pressure.

Abstract

We tested the short-term efficacy and feasibility of two stress education approaches toe the treatment of mild hypertension in older African Americans. This was a randomized, controlled, single-blind trial with 3 months of follow-up in primary care, inner-city health center. Of 213 African American men and women screened, 127 individuals (aged 55 to 85 years with initial diastolic pressure of 90 to 109 mm Hg, systolic pressure of < or = 189 mm Hg, and final baseline blood pressure of < or = 179/104 mm Hg) were selected. Of these, 16 did not complete follow-up blood pressure measurements. Mental and physical stress reduction approaches (Transcendental Meditation and progressive muscle relaxation) were compared with a lifestyle modification education control program and with each other. The primary outcome measures were changes in clinic diastolic and systolic pressures from baseline to final follow-up, measured by blinded observers. The secondary measures were linear blood pressure trends, changes in home blood pressure, and intervention compliance. Adjusted for significant baseline differences and compared with control, Transcendental Meditation reduced systolic pressure by 10.7 mm Hg (P < .0003) and diastolic pressure by 6.4 mm Hg (P <.00005). Progressive muscle relaxation lowered systolic pressure by 4.7 mm Hg (P = 0054) and diastolic pressure by 3.3 mm Hg (P <.02). The reductions in the Transcendental Meditation group were significantly greater than in the progressive muscle relaxation group for both systolic blood pressure (P = .02) and diastolic blood pressure (P = .03). Linear trend analysis confirmed these patterns.(ABSTRACT TRUNCATED AT 250 WORDS)

Comparable studies

Other randomized controlled trials on meditation, most cited first.

Study Year Design Participants
Alterations in Brain and Immune Function Produced by Mindfulness Meditation Healthy employees in a work environment 2003 Randomized controlled trial n = 41
Prevention of relapse/recurrence in major depression by mindfulness-based cognitive therapy. Recovered recurrently depressed patients 2000 Randomized controlled trial n = 145
Open hearts build lives: Positive emotions, induced through loving-kindness meditation, build consequential personal resources. Working adults 2008 Randomized controlled trial n = 139
Short-term meditation training improves attention and self-regulation Undergraduate Chinese students 2007 Randomized controlled trial n = 40
Mindfulness-Based Cognitive Therapy for Depression: Replication and Exploration of Differential Relapse Prevention Effects. Recovered recurrently depressed patients 2004 Randomized controlled trial n = 73

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