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The Research Domain Criteria (RDoC) and the Five Aggregates (skandha-s) of the Early Buddhism: Parallels and Differences on Understanding of Human Mind.

Sung Yong Kang, Soonjo Hwang

Clinical Psychopharmacology and Neuroscience August 27, 2026 DOI: 10.9758/cpn.26.1421 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Theoretical or philosophical paper Peer reviewed
Topics Buddhism
Keywords Mindfulness-based interventions Research domain criteria Dimensional approach Early buddhism Five aggregates <i>skandha</i>-s
Key points Argues that the RDoC framework and early Buddhism's five aggregates (skandha-s) both conceptualize the mind as the collective operation of decentralized systems, and that this convergence carries clinical and practical value for incorporating early Buddhist theory and data into mindfulness-based interventions.

Abstract

The research domain criteria (RDoC) was launched by the National Institute of Mental Health (NIMH) to provide a framework towards development of neurobiological models and novel treatment methods for mental health disorders. Here we elucidate the possible parallels between the RDoC and the understanding of human mind by the early Buddhism, conceptualized as the five aggregates (skandha-s). They both define the function of human mind as a collective operation of de-centralized systems. The state-of-art neuroscience and the long tradition of empirical observation and practice of introspection converges on human mind as division into dimensional sub-sets that can sometime coordinate but often do not. We argue that this similarity not only brings academic interest, but also clinical and practical purposes of incorporating the theoretical framework and empirical data of the early Buddhism into the daily execution of tools originated from this tradition, including the mindfulness-based interventions (MBIs).

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