Self-Disorders and Clinical High Risk for Psychosis: An Empirical Study in Help-Seeking Youth Attending Community Mental Health Facilities.
Andrea Raballo, Elena Pappagallo, Alice Dell' Erba, Nella Lo Cascio, Martina Patane', Eva Gebhardt, Tommaso Boldrini, Laura Terzariol, Massimiliano Angelone, Alberto Trisolini, Paolo Girardi, Paolo Fiori Nastro
Schizophrenia Bulletin January 12, 2016 DOI: 10.1093/schbul/sbv223 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Observational cross-sectional study Peer reviewed |
|---|---|
| Sample size | 47 |
| Population | Adolescent and young adult help-seekers aged 14-25 at putative risk for psychosis attending community mental health facilities in Italy |
| Measures | Structured Interview for Prodromal Syndromes/Scale of Prodromal Symptoms (SIPS/SOPS), Schizophrenia Proneness Instrument-Adult/Child and Youth (SPI-A/CY), Global Assessment of Functioning |
| Keywords | Humans Perceptual disorders Mental disorders Psychotic disorders Schizophrenia Adolescent Female Young adult Prodromal symptoms Psychosis Self Positive symptoms Prodrome Basic symptoms Subjective experience Clinical high risk |
| Key findings | Self-disorder aggregated in Clinical High Risk subjects compared with non-CHR participants and was substantially associated with sub-psychotic symptoms, basic symptoms, and lower global functioning. Combining CHR and SD assessments identified a subgroup of CHR individuals with lower global functioning, which the authors say confirms SD's relevance for early profiling of youths at potential high risk for psychosis. |
Abstract
Anomalous subjective experiences involving an alteration of the basic sense of self (ie, Self-disorder [SD]) are emerging as a core marker of schizophrenia spectrum disorders with potential impact on current early detection strategies as well. In this study, we wished to field-test the prevalence of SD in a clinical sample of adolescent/young adult help-seekers at putative risk for psychosis attending standard community mental health facilities in Italy. Participants (n = 47), aged between 14 and 25, underwent extensive psychopathological evaluations with current semi-structured tools to assess Clinical High Risk (CHR) state (ie, Structured Interview for Prodromal Syndromes/Scale of Prodromal Symptoms [SIPS/SOPS], Schizophrenia Proneness Instrument-Adult/Child and Youth [SPI-A/CY]). SD aggregated in CHR subjects as compared to the non-CHR and revealed substantial association with sub-psychotic symptoms (SIPS), subjective experience of cognitive and cognitive-perceptual vulnerability (basic symptoms) and functional level (Global Assessment of functioning). Moreover, a combination of the 2 approaches (ie, CHR plus SD) enabled further "closing-in" on a subgroup of CHR with lower global functioning. The results confirm SD's relevance for the early profiling of youths at potential high risk for psychosis.
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- The self, neuroscience and psychosis study: Testing a neurophenomenological model of the onset of psychosis Early Intervention in Psychiatry July 2, 2023
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Cites 7
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- Self-disorders and the schizophrenia spectrum: a study of 100 first hospital admissions. Schizophrenia Bulletin January 29, 2014
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- Examination of anomalous self-experience in first-episode psychosis: interrater reliability. Psychopathology August 17, 2011
- A disappearing heritage: the clinical core of schizophrenia. Schizophrenia Bulletin July 19, 2011
and 2 more in the library