Self‐experience in the early phases of schizophrenia: 5‐year follow‐up of the Copenhagen Prodromal Study
Josef Parnas, Andrea Raballo, Peter Handest, Lennart Jansson, Anne Vollmer-Larsen, Ditte Sæbye
World Psychiatry October 1, 2011 DOI: 10.1002/j.2051-5545.2011.tb00057.x (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Prospective observational cohort study Peer reviewed |
|---|---|
| Sample size | 151 |
| Population | First-admission patients in a putative state of beginning psychosis |
| Duration | 60-month follow-up |
| Citations | 175 |
| Key findings | Over 60 months, 37% of first-admission patients in a putative state of beginning psychosis converted to a schizophrenia spectrum diagnosis, and 25% of those with schizotypal disorder converted to schizophrenia. High baseline perplexity and self-disorder scores best predicted later schizophrenia spectrum disorders, while escalating transitions within the spectrum were not associated with any candidate psychopathological predictor. |
Abstract
Despite the avalanche of empirical data on prodromal/"at risk" conditions, the essential aspects of the vulnerability to the schizophrenia spectrum remain largely unaddressed. We report here the results of the Copenhagen Schizophrenia Prodromal Study, a prospective, observational study of first admission patients in putative state of beginning psychosis (N=151) with a follow-up length of 60 months. At follow-up, the rate of conversion to schizophrenia spectrum diagnosis was 37%, whereas the conversion rate from schizotypal disorder to schizophrenia was 25%. High levels of perplexity and self-disorders baseline scores yielded the best prediction of the subsequent development of schizophrenia spectrum disorders. Escalating transitions within the spectrum (i.e., from schizotypal disorder to schizophrenia) were not associated to any candidate psychopathological predictor.
Citations in the library
Cited by 34
- The lived experience of psychosis: a bottom-up review co-written by experts by experience and academics. World Psychiatry June 1, 2022
- Self-disturbance and schizophrenia: structure, specificity, pathogenesis (Current issues, New directions). Schizophrenia Research 2014
- The crisis of minimal self-awareness in schizophrenia: a meta-analytic review. Schizophrenia Research 2014
- Anomalous self-experience in depersonalization and schizophrenia: a comparative investigation. Consciousness and Cognition June 1, 2013
- Mysticism and schizophrenia: A phenomenological exploration of the structure of consciousness in the schizophrenia spectrum disorders. Consciousness and Cognition July 1, 2016
and 29 more in the library
Cites 3
- Looking at the schizophrenia spectrum through the prism of self-disorders: an empirical study. Schizophrenia Bulletin June 15, 2009
- Anomalous Subjective Experience among First-Admitted Schizophrenia Spectrum Patients: Empirical Investigation Psychopathology 2005
- Schizophrenia, consciousness, and the self. Schizophrenia Bulletin 2003