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Autism and perplexity: a qualitative and theoretical study of basic subjective experiences in schizophrenia.

Mads G Henriksen, Borut Škodlar, Louis Sass, Josef Parnas

Psychopathology August 25, 2010 DOI: 10.1159/000320350 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Qualitative single-case study Case report Peer reviewed
Sample size 1
Population One patient with schizophrenia
Topics Anxiety
Keywords Humans Social behavior Self concept Schizophrenia Schizophrenic psychology Adult Male
Key findings The authors report that their patient's self-world relation was profoundly disturbed, characterized by enduring and pervasive experiences of estrangement, anxiety, and exposure that they argue were generative for other symptoms. They propose these experiences as experiential correlates of schizotypy and vulnerability to schizophrenia, potentially useful in early detection, differential diagnosis, and psychotherapy.

Abstract

Background: Autistic traits and perplexity are considered core features of schizophrenia in phenomenological psychiatry. They express a fundamental disturbance of the self-world relation (including disturbances of self and intersubjectivity). The aim of our study was to examine this disturbance by exploring in detail how autism and perplexity are experienced subjectively.

Methods: It is a qualitative single-case study. In order to fully examine our patient's experiences within the context of his experiential world and not only as isolated or decontextualized symptoms, we applied a heideggerian framework, i.e. Heidegger's exhaustive account of the self-world relation (care).

Results: Through the framework of care, we discovered a profound disturbance of the self-world relation in our patient, characterized by subtle experiences of estrangement, anxiety and exposure. We found these experiences to be enduring, pervasive and generative for the development of other symptoms.

Conclusions: We argue that these experiences can be seen as experiential correlates of schizotypy and of vulnerability to schizophrenia, and furthermore that an understanding of these experiences can play a role in diagnostic and differential diagnostic procedures, e.g. in early detection or in the search for high-risk individuals, as well as in the psychotherapy of schizophrenia.

Comparable studies

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Study Year Design Participants
Persistent Palinopsia Following Ingestion of Lysergic Acid Diethylamide (LSD) Patients who developed persistent palinopsia after LSD ingestion 1996 Case series n = 3
Cannabis‐induced Koro in Americans American men aged 22-26 with years of cannabis experience who reported negative... 2001 Case series n = 3
Psilocybin and Obsessive Compulsive Disorder Individual with Obsessive Compulsive Disorder 2014 Case study n = 1
LSD-Like Panic From Risperidone in Post-LSD Visual Disorder Patients with hallucinogen-persisting perception disorder (HPPD) 1996 Case study n = 3
Ketamine-Enhanced Psychotherapy: Preliminary Clinical Observations on its Effects in Treating Death Anxiety Terminally-ill people suffering death anxiety 2007 Review and case study n = 2

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