Revisión sobre el consumo de cannabis como factor de riesgo de la esquizofrenia
Adicciones June 1, 2007 DOI: 10.20882/adicciones.316 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Review Peer reviewed |
|---|---|
| Population | Young people; cohort study participants; individuals with genetic or psychosocial vulnerability to psychosis |
| Topics | Cannabis |
| Citations | 13 |
| Key findings | The authors argue that cannabis use is associated with inducing psychotic symptoms and may act as a risk factor for schizophrenia in people with genetic or psychosocial vulnerability, though existing cohort studies have methodological limitations. They propose that prevention efforts should focus on heavy cannabis users and those who begin use in adolescence. |
Abstract
Cannabis use is extremely prevalent in young people and there is controversy over the psychosocial harm of this use. One risk stands out--that of the possibility of cannabis being a risk factor of an illness as serious and incapacitating as schizophrenia. An avalanche of information has emerged recently on this subject, which it is essential to review. There are a number of cohort studies that support the idea of cannabis use as inducing psychotic symptoms and a precipitating factor of schizophrenia. These studies haves some methodological limitations, which we subject to critical analysis, such as the different outcome evaluations, heterogeneity in the measurements of vulnerability to the psychosis, the difficulty in controlling the possible confusion factors and the inadequate interpretation of the results obtained. In conclusion, we consider that the use of cannabis is clearly associated with the inducement of psychotic symptoms and is, possibly, a risk factor of schizophrenia in people with a genetic or psychosocial vulnerability, preventive methods being necessary in high-risk groups. These are fundamentally those of users of large quantities of cannabis and those who initiate use in adolescence.
Comparable studies
Other narrative reviews on cannabis, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| Causal association between cannabis and psychosis: examination of the evidence | 2004 | Review | |
| Cannabis sativa: A comprehensive ethnopharmacological review of a medicinal plant with a long history. General (historical and pharmacological review) | 2018 | Review | |
| Psychiatric effects of cannabis | 2001 | Review | |
| Beyond THC: The New Generation of Cannabinoid Designer Drugs | 2011 | Review | |
| Cannabidiol, a Cannabis sativa constituent, as an antipsychotic drug | 2006 | Review |
Citations in the library
Cited by 2
Cites 14
- Causal association between cannabis and psychosis: examination of the evidence The British Journal of Psychiatry January 30, 2004
- Cannabis-induced psychosis and subsequent schizophrenia-spectrum disorders: follow-up study of 535 incident cases The British Journal of Psychiatry November 30, 2005
- The link between cannabis use and psychosis: furthering the debate Psychological Medicine December 23, 2002
- Two cases of "cannabis acute psychosis" following the administration of oral cannabis BMC Psychiatry December 1, 2005
- Delta-9-tetrahydrocannabinol effects in schizophrenia: implications for cognition, psychosis, and addiction. Biological Psychiatry March 15, 2005
and 9 more in the library