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Psychotic Reactions Following Cannabis Use in East Indians

Gurbakhsh Singh Chopra

Archives of General Psychiatry 1974 DOI: 10.1001/archpsyc.1974.01760070014002 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Descriptive report (case series of clinical observations) Case report Peer reviewed
Sample size 200
Population Patients at an Indian drug addiction clinic who developed acute cannabis-related psychosis
Intervention Cannabis preparations
Topics Cannabis
Citations 193
Key findings Among 200 patients with acute cannabis psychosis, 45% had no previous psychopathology and most fully recovered; those with severe preexisting pathology sometimes had a less favorable course with schizophrenic and paranoid symptoms. Cannabis potency and dosage schedule, and younger age, were generally related to psychosis occurrence, and 16% developed symptoms from low-potency drug, especially the least stable patients.

Abstract

In a descriptive report of observations carried out in an Indian drug addiction clinic, 200 patients with a characteristic, transient, and acute drug psychosis were observed following the use of cannabis preparations. Of the patients, 45% had no previous psychopathology. Most patients fully recovered. Among those with the most severe preexisting pathology some patients had a less favorable course; drug psychoses in this group occasionally were dominated by schizophrenic and paranoid symptoms. Potency and dosage schedule of cannabis, as well as a younger age, were generally related to occurrence of a toxic psychosis. In 16%, and especially among the least stable patients, low potency drug produced symptoms. There were some relationships between purpose of drug consumption, emotional stability, and demographic variables; for the emotionally stable, "sociability" was a dominant motive. There was no direct association with criminal activity.

Comparable studies

Other case reports and case series on cannabis, most cited first.

Study Year Design Participants
Psychiatric effects of cannabis use Swedish cases of cannabis psychosis 1985 Case series n = 70
Forty-Six Cases of Psychosis in Cannabis Abusers Gunila Bernhardson Habitual cannabis users treated for psychosis at Swedish psychiatric clinics and mental... 1972 Case series (retrospective survey of psychiatric records) n = 46
Hallucinogen persisting perception disorder after psilocybin consumption: a case study 18-year-old man with HPPD after mixed psilocybin and cannabis intoxication 2005 Case study n = 1
Cannabis‐induced Koro in Americans American men aged 22-26 with years of cannabis experience who reported negative... 2001 Case series n = 3
“Hallucinations” Following Acute Cannabis Dosing: A Case Report and Comparison to Other Hallucinogenic Drugs Healthy 30-year-old male 2018 Case study n = 1

Citations in the library

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