What are the neurocognitive correlates of basic self-disturbance in schizophrenia? Integrating phenomenology and neurocognition: Part 2 (aberrant salience).
B Nelson, Thomas J Whitford, Suzie Lavoie, Louis Sass
Schizophrenia Research January 2014 DOI: 10.1016/j.schres.2013.06.033 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Theoretical or philosophical paper Peer reviewed |
|---|---|
| Topics | Philosophy of mind |
| Keywords | Neurocognition Psychosis Schizophrenia Self |
| Key points | Argues that subjective anomalies of basic self-disturbance in schizophrenia may be associated with aberrant salience and related disturbances of memory, prediction, and attention, which could contribute to hyper-reflexivity, disrupted 'grip' on experience, and impaired intuitive social understanding. Calls for empirical studies to test these proposed links between phenomenological and neurocognitive levels. |
Abstract
Phenomenological research indicates that disturbance of the basic sense of self may be a core phenotypic marker of schizophrenia spectrum disorders. Basic self-disturbance refers to disruption of the sense of ownership of experience and agency of action and is associated with a variety of anomalous subjective experiences. Little is known about the neurocognitive underpinnings of basic self-disturbance. In these two theoretical papers (of which this is Part 2), we review some recent phenomenological and neurocognitive research and point to a convergence of these approaches around the concept of self-disturbance. Specifically, we propose that subjective anomalies associated with basic self-disturbance may be associated with: 1. source monitoring deficits, which may contribute particularly to disturbances of "ownership" and "mineness" (the phenomenological notion of presence or self-affection) and 2. aberrant salience, and associated disturbances of memory, prediction and attention processes, which may contribute to hyper-reflexivity, disturbed "grip" or "hold" on perceptual and conceptual fields, and disturbances of intuitive social understanding ("common sense"). In this paper (Part 2) we focus on aberrant salience. Part 1 (this issue) addressed source monitoring deficits. Empirical studies are required in a variety of populations in order to test these proposed associations between phenomenological and neurocognitive aspects of self-disturbance in schizophrenia. An integration of findings across the phenomenological and neurocognitive "levels" would represent a significant advance in the understanding of schizophrenia and possibly enhance early identification and intervention strategies.
Comparable studies
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Citations in the library
Cited by 37
- Looking for the Self: Phenomenology, Neurophysiology and Philosophical Significance of Drug-induced Ego Dissolution Frontiers in Human Neuroscience May 23, 2017
- Self-disturbance and schizophrenia: structure, specificity, pathogenesis (Current issues, New directions). Schizophrenia Research 2014
- Mysticism and schizophrenia: A phenomenological exploration of the structure of consciousness in the schizophrenia spectrum disorders. Consciousness and Cognition July 1, 2016
- The neurophenomenology of early psychosis: An integrative empirical study. Consciousness and Cognition November 1, 2019
- Phenomenological and neurocognitive perspectives on delusions: A critical overview. World Psychiatry June 1, 2015
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Cites 9
- Psychosis as a state of aberrant salience: a framework linking biology, phenomenology, and pharmacology in schizophrenia. American Journal of Psychiatry 2003
- From dopamine to salience to psychosis--linking biology, pharmacology and phenomenology of psychosis. Schizophrenia Research November 1, 2005
- Self-disturbance and schizophrenia: structure, specificity, pathogenesis (Current issues, New directions). Schizophrenia Research 2014
- The phenomenology of the psychotic break and Huxley's trip: substance use and the onset of psychosis. Psychopathology 2008
- What are the neurocognitive correlates of basic self-disturbance in schizophrenia?: Integrating phenomenology and neurocognition. Part 1 (Source monitoring deficits). Schizophrenia Research January 2014
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