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Studying hallucinations within the NIMH RDoC framework.

Judith M. Ford, Sarah E Morris, Ralph E Hoffman, Iris E C Sommer, Flavie Waters, Simon McCarthy-Jones, Robert J Thoma, Jessica A. Turner, Sarah Keedy, Johanna C Badcock, Bruce N Cuthbert

Schizophrenia Bulletin July 2014 DOI: 10.1093/schbul/sbu011 (opens in new tab)

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AI-extracted from the abstract
Characteristics Theoretical or philosophical paper Peer reviewed
Keywords Criteria Domain Rdoc Hallucinations
Key points Proposes that hallucinations be studied through the RDoC framework's basic dimensions of functioning rather than symptom-based diagnoses, and raises the question of whether hallucinations in nonclinical populations are the same phenomenon as those in psychotic diagnoses. Argues that applying RDoC to hallucinations faces challenges and outlines potential next steps.

Abstract

We explore how hallucinations might be studied within the National Institute of Mental Health (NIMH) Research Domain Criteria (RDoC) framework, which asks investigators to step back from diagnoses based on symptoms and focus on basic dimensions of functioning. We start with a description of the objectives of the RDoC project and its domains and constructs. Because the RDoC initiative asks investigators to study phenomena across the wellness spectrum and different diagnoses, we address whether hallucinations experienced in nonclinical populations are the same as those experienced by people with psychotic diagnoses, and whether hallucinations studied in one clinical group can inform our understanding of the same phenomenon in another. We then discuss the phenomenology of hallucinations and how different RDoC domains might be relevant to their study. We end with a discussion of various challenges and potential next steps to advance the application of the RDoC approach to this area of research.

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