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A randomized controlled trial comparing Mindfulness and Heartfulness meditation programmes on stress, anxiety, depressive symptoms and wellbeing among distance-learning postgraduates

Diana Brito Pearmain, Mark Kennedy, Karoly Schlosser

Frontiers in Psychology September 17, 2026 DOI: 10.3389/fpsyg.2026.1810901 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Randomized controlled trial Peer reviewed
Sample size 73
Population UK-based and international distance-learning postgraduate (master's and doctorate) students at King's College London; 61 completed questionnaires (80% female)
Interventions Mindfulness-based intervention (MBI) Heartfulness-based intervention (HBI)
Duration 8-week intervention with 12-week follow-up
Topics Anxiety Depression Meditation
Keywords Heartfulness Postgraduate students Remote intervention
Key findings The group × time interaction was not statistically significant for primary outcomes, indicating no differential change between the Mindfulness-based and Heartfulness-based interventions. Both interventions were associated with significant within-group improvements in stress, anxiety, depressive symptoms and wellbeing after eight weeks, with wellbeing and stress gains maintained at twelve-week follow-up; anxiety reductions were sustained only in per-protocol analysis.

Abstract

BackgroundPostgraduate students are six times more susceptible to mental health challenges than the general adult population, making it imperative to identify effective initiatives to support them. This is particularly relevant for master’s and doctorate students undertaking distance-learning programmes as this is a dimension of the student experience that remains unexplored. Meditation practices such as those included in Mindfulness and Heartfulness programmes have been shown to improve university students’ mental health and wellbeing even when delivered via videoconferencing. However, the efficacy of these approaches remains under-investigated among distance learning postgraduates.ObjectivesThis study aims to explore the impact of an online synchronous Mindfulness-based intervention (MBI) compared to a Heartfulness-based intervention (HBI) on distance-learning postgraduate students’ mental health and wellbeing using randomised controlled trial (RCT) design.MethodsThe MBI included guided meditations, emphasizing present moment focus through breathwork and body scan exercises, compassion and non-judgmental observations. The HBI included a heart-focused form of silent meditation, with additional mental exercises aimed to facilitate the clearing and release of impressions. Weekly live online instructor-led group sessions facilitated access across 17 countries on six continents. In an initially powered RCT using block randomisation, N = 73 UK-based and international postgraduate students from King’s College London (KCL) were allocated to either HBI (n = 37) or MBI (n = 36). 61 (80% female) completed validated questionnaires at baseline (T1), after 8-week intervention (T2) and at twelve-week follow-up (T3) through intention-to-treat (ITT) analysis. Significance was assessed through repeated-measures ANOVA, supplemented by mixed-effects modeling to assess robustness.ResultsIn line with hypotheses, the group × time interaction was not statistically significant for primary outcomes, providing no indication of differential change between interventions. Both MBI and HBI were associated with significant improvements in stress, anxiety, depressive symptoms and wellbeing in postgraduates over time, established through secondary within-group outcomes at T2. At T3, improvements were maintained for wellbeing and stress through ITT analysis. Anxiety reductions were sustained only through Per-Protocol (PP) analysis at T3.ConclusionThese findings are consistent with comparable effects. Both HBI and MBI may be beneficial as preventative and transdiagnostic approaches for postgraduate students’ mental health and wellbeing, at scale, and remotely with a global reach.

Comparable studies

Other randomized controlled trials on anxiety, most cited first.

Study Year Design Participants
Prevention of relapse/recurrence in major depression by mindfulness-based cognitive therapy. Recovered recurrently depressed patients 2000 Randomized controlled trial n = 145
Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening cancer: A randomized double-blind trial Cancer patients with life-threatening diagnoses and symptoms of depression and/or anxiety 2016 Randomized controlled trial n = 51
Rapid and sustained symptom reduction following psilocybin treatment for anxiety and depression in patients with life-threatening cancer: a randomized controlled trial Patients with cancer-related anxiety and depression 2016 Double-blind, placebo-controlled, crossover trial n = 29
Psilocybin can occasion mystical-type experiences having substantial and sustained personal meaning and spiritual significance Hallucinogen-naïve adults reporting regular participation in religious or spiritual... 2006 Double-blind study n = 36
Pilot Study of Psilocybin Treatment for Anxiety in Patients With Advanced-Stage Cancer Adults with advanced-stage cancer and anxiety 2010 Double-blind, placebo-controlled study n = 12

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