A Randomized Controlled Pilot Study on the Effects of Loving-Kindness and Mindfulness Meditation (LKM) on Patients in a Sterile Isolation Room to Improve Their Mood Status
Shinobu Yamada, Kohki Arimitsu, Momoko Buyo, Tomoyo Mukai, Rie Noguchi, Akiko Misu, Takashi Sonoki, Makiko Hayashi
Japanese Journal of Complementary and Alternative Medicine August 31, 2025 DOI: 10.1625/jcam.22.9 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Randomized controlled trial Pilot study Peer reviewed |
|---|---|
| Sample size | 9 |
| Population | Hematologic malignancy patients in a sterile isolation room |
| Duration | 20-minute video intervention; POMS2 measured before intervention and one and two weeks after intervention |
| Measures | POMS2 Japanese version |
| Topics | Meditation |
| Key findings | The abstract describes a randomized controlled trial of a 20-minute Loving-Kindness and Mindfulness Meditation video for mood improvement in nine hematologic malignancy patients in sterile isolation. It reports the design, intervention, and POMS2 assessment schedule but does not state the trial's results or conclusions, so whether the intervention improved mood is not reported in the available text. |
Abstract
Objective: This study investigates the effectiveness of the Loving-Kindness and Mindfulness Meditation (LKM) therapy in improving mood states of hematologic malignancy patients in a sterile isolation room.A randomized controlled trial was conducted, with the POMS2 Japanese version used to assess mood state improvement.Methods: The final number of participants in this study was nine (intervention group n=4, control group n=5).Patients in a sterile isolation room were provided with a tablet containing a video of the LKM.The intervention group watched the 20-minute video.POMS2 factor scores were measured before the intervention and again one and two weeks after the intervention.The data
Comparable studies
Other randomized controlled trials on meditation, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| Alterations in Brain and Immune Function Produced by Mindfulness Meditation Healthy employees in a work environment | 2003 | Randomized controlled trial | n = 41 |
| Prevention of relapse/recurrence in major depression by mindfulness-based cognitive therapy. Recovered recurrently depressed patients | 2000 | Randomized controlled trial | n = 145 |
| Open hearts build lives: Positive emotions, induced through loving-kindness meditation, build consequential personal resources. Working adults | 2008 | Randomized controlled trial | n = 139 |
| Short-term meditation training improves attention and self-regulation Undergraduate Chinese students | 2007 | Randomized controlled trial | n = 40 |
| Mindfulness-Based Cognitive Therapy for Depression: Replication and Exploration of Differential Relapse Prevention Effects. Recovered recurrently depressed patients | 2004 | Randomized controlled trial | n = 73 |
Citations in the library
Cites 12
- Loving-kindness and compassion meditation: potential for psychological interventions. Clinical Psychology Review July 26, 2011
- The effect of loving-kindness meditation on positive emotions: a meta-analytic review Frontiers in Psychology November 3, 2015
- Mindfulness-based interventions for addictive behaviors: Implementation issues on the road ahead. Psychology of Addictive Behaviors October 26, 2017
- Effects of a 12-Minute Smartphone-Based Mindful Breathing Task on Heart Rate Variability for Students With Clinically Relevant Chronic Pain, Depression, and Anxiety: Protocol for a Randomized Controlled Trial. JMIR Research Protocols December 2, 2019
- A meta-analytic investigation of the impact of mindfulness-based interventions on ADHD symptoms Medicine June 1, 2019
and 7 more in the library