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Benefícios da psicoterapia assistida por MDMA para pacientes diagnosticados com TEPT

Gustavo Souza Fioroti, Natália Corassa Pinheiro, Fábio Nogueira Pereira

Revista Científica Faesa June 1, 2024 DOI: 10.5008/1809.7367.272 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Theoretical or philosophical paper Double-blind Peer reviewed
Population Patients diagnosed with post-traumatic stress disorder (PTSD)
Topics MDMA
Key points Argues that MDMA-assisted psychotherapy may be a safe and effective clinical option for PTSD, citing double-blind studies in which some participants received MDMA and others placebo alongside psychotherapy; the authors report significant results and efficacy even for treatment-resistant conditions.

Abstract

This essay discusses the potential clinical use of 3,4methylenedioxymethamphetamine (MDMA) with patients diagnosed with Post Traumatic Stress Disorder (PTSD). We present a brief history of the use of consciousness-altering substances from ancient times to the present as well as recent research on psychedelic assisted psychotherapy (PAP). Double blind investigation in which some of the participants received MDMA and others placebo as an assistant to their psychotherapy process. Results in several studies revealed significant results, a high profile of safety and efficacy even for the treatment of resistant conditions.

Comparable studies

Other theoretical and historical papers on MDMA, most cited first.

Study Year Design Participants
Differences Between the Mechanism of Action of MDMA, MBDB, and the Classic Hallucinogens. Identification of a New Therapeutic Class: Entactogens 1986 Theoretical or philosophical paper
The Background and Chemistry of MDMA 1986 Historical analysis
The origin of MDMA (ecstasy) revisited: the true story reconstructed from the original documents* Original documents in Merck's historical archive in Darmstadt, Germany, years 1900–1960 2006 Historical analysis
Distinct neural mechanisms for the prosocial and rewarding properties of MDMA 2019 Theoretical or philosophical paper
How could MDMA (ecstasy) help anxiety disorders? A neurobiological rationale 2009 Theoretical or philosophical paper

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