Rhabdomyolysis After LSD Ingestion.
Zachary Berrens, Jessica Lammers, Christopher G. White
Psychosomatics 2010 DOI: 10.1176/appi.psy.51.4.356 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Case report and literature review Peer reviewed |
|---|---|
| Sample size | 1 |
| Population | A previously healthy patient who ingested LSD |
| Topics | LSD |
| Key findings | LSD-associated rhabdomyolysis is rarely reported despite being frequently listed as a cause. The new case adds to the limited evidence, and the authors outline mechanisms and management, emphasizing the role of consultation psychiatrists in addressing agitation and facilitating addiction treatment. |
Abstract
Rhabdomyolysis involves the release of intracellular contents secondary to muscle cell injury; it generally presents with muscle pain and weakness. Illicit drugs, including phencyclidine, MDMA ("ecstasy"), and cocaine, are frequently documented as a cause of rhabdomyolysis. The authors review the literature on LSD-associated rhabdomyolysis. The authors provide a new case report of a previously health patient who suffered rhabdomyolysis after LSD ingestion. Although frequently listed as a cause of rhabdomyolysis, there are only limited reports of rhabdomyolysis in patients who have ingested LSD. The discussion outlines potential mechanisms and management of LSD-associated rhabdomyolysis. Consultation psychiatrists may be called to assist in management of acute mental-status changes or agitation associated with LSD intoxication in addition to facilitating subsequent chemical-dependency treatment.
Comparable studies
Other case reports and case series on LSD, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| Lasting Neuropsychiatric Sequelae of (??)Methylenedioxymethamphetamine (???Ecstasy???) in Recreational Users Persons who ingested large doses of MDMA | 1991 | Case study | n = 2 |
| Further Studies in the Therapeutic Value of Lysergic Acid Diethylamide in Mental Illness Patients with mental illness | 1957 | Case series | |
| Coma, Hyperthermia, and Bleeding Associated with Massive LSD Overdose a Report of Eight Cases People who self-administered large amounts of pure LSD powder intranasally | 1975 | Case series | n = 8 |
| Using a MDMA- and LSD-Group Therapy Model in Clinical Practice in Switzerland and Highlighting the Treatment of Trauma-Related Disorders Patients with chronic complex post-traumatic stress disorder (c-PTSD), dissociative,... | 2022 | Case series | |
| Persistent Palinopsia Following Ingestion of Lysergic Acid Diethylamide (LSD) Patients who developed persistent palinopsia after LSD ingestion | 1996 | Case series | n = 3 |
Citations in the library
Cited by 5
- Psychedelics in Psychiatry: Neuroplastic, Immunomodulatory, and Neurotransmitter Mechanisms Pharmacological Reviews December 16, 2020
- Adolescent and adult time trends in US hallucinogen use, 2002–19: any use, and use of ecstasy, LSD and PCP Addiction August 17, 2022
- Assessing the risk–benefit profile of classical psychedelics: a clinical review of second-wave psychedelic research Psychopharmacology January 13, 2022
- Perceived Risk of Trying Lysergic Acid Diethylamide in the United States from 2015 to 2019: Are Americans Assessing Lysergic Acid Diethylamide's Risk Profile More Favorably? Psychedelic Medicine June 1, 2024
- N,N-Dimethyltryptamine-Induced Psychosis. Clinical Neuropharmacology 2015