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Rhabdomyolysis After LSD Ingestion.

Zachary Berrens, Jessica Lammers, Christopher White

Psychosomatics 2010 DOI: 10.1176/appi.psy.51.4.356 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Case report and literature review Peer reviewed
Sample size 1
Population A previously healthy patient who ingested LSD
Topics LSD
Key findings LSD-associated rhabdomyolysis is rarely reported despite being frequently listed as a cause. The new case adds to the limited evidence, and the authors outline mechanisms and management, emphasizing the role of consultation psychiatrists in addressing agitation and facilitating addiction treatment.

Abstract

Rhabdomyolysis involves the release of intracellular contents secondary to muscle cell injury; it generally presents with muscle pain and weakness. Illicit drugs, including phencyclidine, MDMA ("ecstasy"), and cocaine, are frequently documented as a cause of rhabdomyolysis. The authors review the literature on LSD-associated rhabdomyolysis. The authors provide a new case report of a previously health patient who suffered rhabdomyolysis after LSD ingestion. Although frequently listed as a cause of rhabdomyolysis, there are only limited reports of rhabdomyolysis in patients who have ingested LSD. The discussion outlines potential mechanisms and management of LSD-associated rhabdomyolysis. Consultation psychiatrists may be called to assist in management of acute mental-status changes or agitation associated with LSD intoxication in addition to facilitating subsequent chemical-dependency treatment.