Lysergic Acid Diethylamide and Stimulus Generalization: Rate-Dependent Effects
Linda A. Dykstra, James B. Appel
Science August 25, 1972 DOI: 10.1126/science.177.4050.720 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Experimental study Peer reviewed |
|---|---|
| Population | Rats |
| Intervention | LSD |
| Topics | LSD |
| Key findings | LSD changed the shape of the auditory generalization gradient only at a dose that decreased relatively high response rates, indicating that the drug's effect on stimulus sensitivity may be secondary to its rate-suppressing action. |
Abstract
A stimulus generalization procedure was used to investigate the effects of LSD on sensitivity to auditory stimuli in rats. The shape of the generalization gradient was changed after administration of the drug only with a dose which produced decreases in relatively high rates of responding.