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The Effect of Online Mindfulness-Based Stress Reduction Program on Sleep Quality in Mothers of Children with Autism Spectrum Disorder: A Randomized Clinical Trial.

Fatemeh Miryounesi, Sima Ghezelbash, Mousa Alavi

Iranian Journal of Nursing and Midwifery Research 2026 DOI: 10.4103/ijnmr.ijnmr_22_24 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Randomized single-blinded controlled trial Peer reviewed
Sample size 72
Population Mothers of children with autism spectrum disorder from Fatemeh Zahra and Parnian Autism Centers in Isfahan City, Iran
Intervention Mindfulness-Based Stress Reduction (MBSR) program
Duration Eight 90-minute sessions twice a week, with follow-up one month after intervention
Measures Pittsburgh Sleep Quality Index (PSQI)
Topics Meditation
Keywords Autism spectrum disorder Disease managements Nursing Sleep quality Stress
Key findings MBSR significantly improved sleep quality in mothers of children with ASD immediately after and one month post-intervention, while the control group showed no significant change. The authors conclude that MBSR effectively improves sleep and recommend its integration into healthcare protocols.

Abstract

Mothers of children with autism spectrum disorder (ASD) would experience elevated levels of stress and psychological distress. This study examined the effect of an online Mindfulness-Based Stress Reduction (MBSR) Program on sleep quality in mothers of children with ASD. This was a randomized single-blinded controlled trial that was conducted in 2022 on 72 mothers of children with ASD from Fatemeh Zahra and Parnian Autism Centers in Isfahan City, Iran. Participants were recruited through a convenient sampling and randomly assigned to intervention (n = 36) and control (n = 36) groups. The intervention group underwent eight 90-min MBSR sessions twice a week. Data were collected using a demographic information form and the Pittsburgh Sleep Quality Index (PSQI) at baseline, immediately after, and one month after the intervention. Data were analyzed using independent samples: t-test, Chi-square, and one-way repeated-measure. The intervention group showed significantly improved sleep quality scores immediately after (F = 107.004, P < 0.001) and one month after (F = 107.004, P < 0.001) the intervention compared to the control group (lower PSQI score indicates better sleep quality). Repeated-measure ANOVA indicated a significant change in sleep quality scores over time within the intervention group (F = 107.004, P < 0.05), but no significant change was found in the control group (F = 1.292, P > 0.05). The findings of this study demonstrate that MBSR effectively improves sleep in mothers of children with ASD. Given its cost-effectiveness, MBSR should be integrated into healthcare protocols.

Comparable studies

Other randomized controlled trials on meditation, most cited first.

Study Year Design Participants
Alterations in Brain and Immune Function Produced by Mindfulness Meditation Healthy employees in a work environment 2003 Randomized controlled trial n = 41
Prevention of relapse/recurrence in major depression by mindfulness-based cognitive therapy. Recovered recurrently depressed patients 2000 Randomized controlled trial n = 145
Open hearts build lives: Positive emotions, induced through loving-kindness meditation, build consequential personal resources. Working adults 2008 Randomized controlled trial n = 139
Short-term meditation training improves attention and self-regulation Undergraduate Chinese students 2007 Randomized controlled trial n = 40
Mindfulness-Based Cognitive Therapy for Depression: Replication and Exploration of Differential Relapse Prevention Effects. Recovered recurrently depressed patients 2004 Randomized controlled trial n = 73

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