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Effects of Compassion Meditation on Psychological Status in Patients With Diabetes: A Pilot Randomized Controlled Trial

Seongkum Heo, Tammy Barbé, Justus Randolph, JinShil Kim

Western Journal of Nursing Research June 29, 2026 DOI: 10.1177/01939459261454836 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Pilot randomized controlled trial Peer reviewed
Sample size 46
Population Patients with type 1 or type 2 diabetes
Intervention Compassion meditation
Duration 4-week intervention, 4-week follow-up
Topics Meditation
Key findings A 4-week compassion meditation intervention improved diabetes self-efficacy and reduced diabetes distress in patients with diabetes compared to a control group.

Abstract

Background: Patients with diabetes often experience significant psychological distress, contributing to poor diabetes self-management and complications. Meditation may reduce psychological distress, but most meditation interventions have been lengthy and burdensome to both participants and interventionists.

Purpose: The purpose of this study was to evaluate the preliminary effects of a 4-week compassion meditation intervention with recorded Zoom sessions (30-40 minutes/session) on psychological factors (depressive symptoms, diabetes distress, self-compassion, resilience, self-esteem, and self-efficacy) in patients with type 1 or type 2 diabetes.

Methods: In this pilot randomized controlled trial, participants were recruited via ResearchMatch. Baseline and 4-week follow-up data on all the study variables and demographic characteristics were collected via Research Electronic Data Capture from April to July 2025. After baseline, each participant was randomly assigned to the intervention or control group based on a computer-generated list of random numbers. Independent samples t -tests, Mann-Whitney U tests, paired samples t -tests, Wilcoxon signed-rank tests, and analysis of covariance were used for data analysis.

Results: Between-group analyses showed higher levels of diabetes self-efficacy and lower diabetes distress in the intervention group ( n = 17, mean age: 51.8 years) at 4-week follow-up compared with the control group ( n = 29, mean age: 51.7 years). Within-group analyses showed reductions in diabetes distress and improvements in self-compassion and self-efficacy in the intervention group, while self-esteem decreased in the control group from baseline to follow-up.

Conclusions: This brief, virtual compassionate meditation intervention showed favorable effects on several psychological factors. It may be implemented to enhance psychological statuses in patients with diabetes.

Comparable studies

Other randomized controlled trials on meditation, most cited first.

Study Year Design Participants
Alterations in Brain and Immune Function Produced by Mindfulness Meditation Healthy employees in a work environment 2003 Randomized controlled trial n = 41
Prevention of relapse/recurrence in major depression by mindfulness-based cognitive therapy. Recovered recurrently depressed patients 2000 Randomized controlled trial n = 145
Open hearts build lives: Positive emotions, induced through loving-kindness meditation, build consequential personal resources. Working adults 2008 Randomized controlled trial n = 139
Short-term meditation training improves attention and self-regulation Undergraduate Chinese students 2007 Randomized controlled trial n = 40
Mindfulness-Based Cognitive Therapy for Depression: Replication and Exploration of Differential Relapse Prevention Effects. Recovered recurrently depressed patients 2004 Randomized controlled trial n = 73

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