Factors associated with relapse and recurrence of major depressive disorder in patients starting mindfulness‐based cognitive therapy
J. D. de Klerk-Sluis, Marloes J. Huijbers, S. Löcke, Jan Spijker, Philip Spinhoven, Anne E. M. Speckens, Henricus G. Ruhé
Depression and Anxiety November 9, 2021 DOI: 10.1002/da.23220 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Review Peer reviewed |
|---|---|
| Topics | Depression Meditation |
| Key findings | Argues that the association of cognitive reactivity, rumination, self-compassion, and mindfulness with relapse before initiation of MBCT has never been investigated. |
Abstract
Mindfulness‐based cognitive therapy (MBCT) is effective for relapse prevention in major depressive disorder (MDD). It reduces cognitive reactivity (CR) and rumination, and enhances self‐compassion and mindfulness. Although rumination and mindfulness after MBCT are associated with relapse, the association of CR, rumination, self‐compassion, and mindfulness with relapse before initiation of MBCT has never been investigated.
Comparable studies
Other narrative reviews on depression, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| Synaptic Dysfunction in Depression: Potential Therapeutic Targets | 2012 | Review | |
| Mindfulness-Based Cognitive Therapy for Depression: A New Approach to Preventing Relapse | 2003 | Review | |
| Synthesizing the Evidence for Ketamine and Esketamine in Treatment-Resistant Depression: An International Expert Opinion on the Available Evidence and Implementation Adults with treatment-resistant depression | 2021 | Review | |
| Classic psychedelics: An integrative review of epidemiology, therapeutics, mystical experience, and brain network function. General population | 2019 | Integrative review | |
| Sudarshan Kriya Yogic Breathing in the Treatment of Stress, Anxiety, and Depression: Part II—Clinical Applications and Guidelines | 2005 | Review |
Citations in the library
Cited by 4
- Mindfulness-Based Cognitive Therapy in Clinical Practice: A Systematic Review of Neurocognitive Outcomes and Applications for Mental Health and Well-Being. Journal of Clinical Medicine March 3, 2025
- A randomized controlled trial of mindfulness-based cognitive therapy for major depressive disorder in undergraduate students: Dose- response effect, inflammatory markers and BDNF. Psychiatry Research 2024
- Evaluating the Efficacy of Mindfulness-Based Cognitive Therapy in Alleviating Depressive Symptoms, Reducing Rumination, and Preventing Relapse Among the Institutionalized Patients in Nigeria: A Randomized Controlled Trial. International Journal of Social Psychiatry December 29, 2025
- The Effectiveness of Mindfulness-Based Cognitive Therapy for Major Depressive Disorder and Relapse Prevention Transactions on Materials, Biotechnology and Life Sciences March 24, 2024
Cites 13
- Using Self-Report Assessment Methods to Explore Facets of Mindfulness Assessment January 27, 2006
- Prevention of relapse/recurrence in major depression by mindfulness-based cognitive therapy. Journal of Consulting and Clinical Psychology 2000
- Mindfulness-Based Cognitive Therapy for Depression: Replication and Exploration of Differential Relapse Prevention Effects. Journal of Consulting and Clinical Psychology 2004
- Treatment-specific changes in decentering following mindfulness-based cognitive therapy versus antidepressant medication or placebo for prevention of depressive relapse. Journal of Consulting and Clinical Psychology March 12, 2012
- Effects of Mindfulness Based Cognitive Therapy (MBCT) and Compassion Focused Therapy (CFT) on Symptom Change, Mindfulness, Self-Compassion, and Rumination in Clients With Depression, Anxiety, and Stress Frontiers in Psychology May 17, 2019
and 8 more in the library