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Free Your Mind and Mental Health and Wellbeing Will Follow: Evidence from Across-Day Within-Person Mediation in an Eight-Week Mindfulness RCT

Paul Verhaeghen, Shelley N. Aikman, Nilam Ram

Mindfulness March 26, 2026 DOI: 10.1007/s12671-026-02820-y (opens in new tab) via OpenAlex

Summary

AI-generated from the abstract

Daily measures from 133 college students in an eight-week mindfulness intervention and 131 waitlist controls showed that state mindfulness improves mental health and wellbeing by reducing rumination and cognitive interference and increasing self-compassion and self-transcendent emotions. Cognitive interference was the strongest mediator. The acceptance facet of mindfulness worked through rumination, cognitive interference, and self-compassion; the monitoring facet worked through self-compassion and self-transcendent emotions. The intervention did not change the strength of these causal pathways. More meditation and mindfulness practice correlated with higher state mindfulness.

Study at a glance

Characteristics Randomized controlled trial Preregistered Peer reviewed
Sample size 264
Population College students
Intervention Mindfulness intervention
Duration Eight-week intervention, daily measures
Topics Meditation
Keywords Mental health Rumination Moderation Moderated mediation Cognition
Key finding Mindfulness improves mental health and wellbeing by reducing rumination and cognitive interference and increasing self-compassion and self-transcendent emotions.

Abstract

Abstract Objectives The study aimed to identify the within-person mediating mechanisms linking state mindfulness to mental health, wellbeing, and compassion. Method Participants (133 college students going through an eight-week mindfulness intervention, and 131 waitlist controls) provided daily measures of predictors (facets of mindfulness), mediators (rumination, cognitive interference, self-compassion, and self-transcendent emotions), and outcomes (mental health, wellbeing, and compassion). One-day lagged within-person mediation models were applied to test for mediation effects. Results We obtained complete or partial mediation for all outcome variables except compassion; cognitive interference was the strongest mediator. Effects of the acceptance facet of mindfulness were mediated through rumination, cognitive interference, and self-compassion; the effects of the monitoring aspect through self-compassion and self-transcendent emotions. Moderation analyses showed that the mindfulness intervention did not modify the strength of existing causal pathways. We also obtained positive correlations between meditation and mindfulness practice and state mindfulness. Conclusions The findings strongly suggest a causal flow of influence, where mindfulness (as enhanced through meditation and informal practices) boosts mental health and wellbeing by reducing rumination and cognitive interference and increasing self-compassion and self-transcendence. Mindfulness thus can free the mind from excessive self-preoccupation, thereby improving mental health and wellbeing. Preregistration : This study is not preregistered.

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