The Effectiveness of Mindfulness-based Cognitive Therapy on Psychological Symptoms and Quality of Life in Systemic Lupus Erythematosus Patients: A Randomized Controlled Trial
Kamal Solati, Mohammad Mousavi, Soleiman Kheiri, Ali Hasanpour-Dehkordi
Oman Medical Journal October 11, 2017 DOI: 10.5001/omj.2017.73 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Randomized single-blind clinical trial Peer reviewed |
|---|---|
| Sample size | 46 |
| Population | Patients with systemic lupus erythematosus referred from Imam Ali Clinic in Shahrekord, southwest Iran |
| Intervention | Mindfulness-based cognitive therapy |
| Duration | Eight group sessions of MBCT; assessment before, after, and six months after intervention |
| Topics | Meditation |
| Keywords | Cognitive therapy Lupus erythematosus Systemic Quality of life |
| Key findings | MBCT significantly decreased psychological symptoms and improved quality of life in SLE patients compared to routine care alone, with stable effects on psychological but not physical components. |
Abstract
Objectives: This study was conducted to determine the efficacy of mindfulness-based cognitive therapy (MBCT) on psychological symptoms and quality of life (QoL) in patients with systemic lupus erythematosus (SLE).
Methods: We conducted a randomized single-blind clinical trial in patients with SLE referred from the Imam Ali Clinic in Shahrekord, southwest Iran. The patients (46 in total in two groups of 23 each) were randomly assigned into the experimental and control groups. Both groups underwent routine medical care, and the experimental group underwent eight group sessions of MBCT in addition to routine care. The patient,s QoL was assessed using the General Health Questionnaire-28 and 36-Item Short Form Health Survey before, after, and six months after intervention (follow-up).
Results: A significant difference was seen in psychological symptoms and QoL between MBCT and control groups immediately after the intervention and at follow-up (p ≤ 0.050). However, the difference was not significant for the physical components of QoL (p ≥ 0.050).
Conclusions: MBCT contributed to decreased psychological symptoms and improved QoL in patients with SLE with a stable effect on psychological symptoms and psychological components of QoL, but an unstable effect on physical components.
Comparable studies
Other randomized controlled trials on meditation, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| Alterations in Brain and Immune Function Produced by Mindfulness Meditation Healthy employees in a work environment | 2003 | Randomized controlled trial | n = 41 |
| Prevention of relapse/recurrence in major depression by mindfulness-based cognitive therapy. Recovered recurrently depressed patients | 2000 | Randomized controlled trial | n = 145 |
| Open hearts build lives: Positive emotions, induced through loving-kindness meditation, build consequential personal resources. Working adults | 2008 | Randomized controlled trial | n = 139 |
| Short-term meditation training improves attention and self-regulation Undergraduate Chinese students | 2007 | Randomized controlled trial | n = 40 |
| Mindfulness-Based Cognitive Therapy for Depression: Replication and Exploration of Differential Relapse Prevention Effects. Recovered recurrently depressed patients | 2004 | Randomized controlled trial | n = 73 |
Citations in the library
Cited by 4
- Mindfulness based interventions for depression and anxiety in Asian Population: A systematic review Journal of Psychiatrists Association of Nepal June 28, 2018
- The Efficacy of Mindfulness-Based Interventions on Depressive Symptoms and Quality of Life: A Systematic Review of Randomized Controlled Trials OBM Integrative and Complementary Medicine June 25, 2018
- Effects of Mindfulness-Based Cognitive Therapy for Chronic Pain: A Multicenter Study International Journal of Environmental Research and Public Health June 29, 2021
- The effectiveness of mindfulness training on coping with stress, exam anxiety, and happiness to promote health Journal of Education and Health Promotion May 31, 2021
Cites 11
- Mindfulness-Based Stress Reduction, Mindfulness-Based Cognitive Therapy, and Zen Meditation for Depression, Anxiety, Pain, and Psychological Distress Journal of Psychiatric Practice July 1, 2012
- Mindfulness-based Stress Reduction (MBSR) Reduces Anxiety, Depression, and Suicidal Ideation in Veterans Medical Care November 13, 2014
- The Efficacy of Mindfulness-Based Cognitive Therapy on Resilience among the Wives of Patients with Schizophrenia. Journal of Clinical and Diagnostic Research April 2017
- Comparison of the acceptability and benefits of two mindfulness-based interventions in women with breast or gynecologic cancer: a pilot study. Supportive Care in Cancer April 2015
- Mindfulness-based cognitive therapy in obsessive-compulsive disorder: protocol of a randomized controlled trial. BMC Psychiatry November 18, 2014
and 6 more in the library