The Effectiveness of Mindfulness-based Cognitive Therapy on Psychological Symptoms and Quality of Life in Systemic Lupus Erythematosus Patients: A Randomized Controlled Trial
Kamal Solati, Mohammad Mousavi, Soleiman Kheiri, Ali Hasanpour-Dehkordi
Oman Medical Journal October 11, 2017 DOI: 10.5001/omj.2017.73 (opens in new tab) via DOAJ
Summary
AI-generated from the abstractMindfulness-based cognitive therapy (MBCT) added to routine medical care reduced psychological symptoms and improved quality of life in patients with systemic lupus erythematosus (SLE) compared with routine care alone. The benefit was stable for psychological symptoms and psychological components of quality of life immediately after the eight-session intervention and at a six-month follow-up, but the effect on physical components of quality of life was not statistically significant and was unstable.
Study at a glance
| Characteristics | Randomized single-blind clinical trial Peer reviewed |
|---|---|
| Sample size | 46 |
| Population | Patients with systemic lupus erythematosus referred from Imam Ali Clinic in Shahrekord, southwest Iran |
| Intervention | Mindfulness-based cognitive therapy |
| Duration | Eight group sessions of MBCT; assessment before, after, and six months after intervention |
| Topics | Meditation |
| Keywords | Cognitive therapy Lupus erythematosus Systemic Quality of life |
| Key finding | MBCT significantly decreased psychological symptoms and improved quality of life in SLE patients compared to routine care alone, with stable effects on psychological but not physical components. |
Abstract
Objectives: This study was conducted to determine the efficacy of mindfulness-based cognitive therapy (MBCT) on psychological symptoms and quality of life (QoL) in patients with systemic lupus erythematosus (SLE). Methods: We conducted a randomized single-blind clinical trial in patients with SLE referred from the Imam Ali Clinic in Shahrekord, southwest Iran. The patients (46 in total in two groups of 23 each) were randomly assigned into the experimental and control groups. Both groups underwent routine medical care, and the experimental group underwent eight group sessions of MBCT in addition to routine care. The patient,s QoL was assessed using the General Health Questionnaire-28 and 36-Item Short Form Health Survey before, after, and six months after intervention (follow-up). Results: A significant difference was seen in psychological symptoms and QoL between MBCT and control groups immediately after the intervention and at follow-up (p ≤ 0.050). However, the difference was not significant for the physical components of QoL (p ≥ 0.050). Conclusions: MBCT contributed to decreased psychological symptoms and improved QoL in patients with SLE with a stable effect on psychological symptoms and psychological components of QoL, but an unstable effect on physical components.