Hyperlocomotion Test for Assessing Behavioral Disorders.
Dan Ma, Paul C Guest
Methods in molecular biology (Clifton, N.J.) 2018 DOI: 10.1007/978-1-4939-7614-0_29 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Protocol Peer reviewed |
|---|---|
| Population | Rats |
| Keywords | Behavioral deficits Hyperlocomotion test Nutritional programming Pcp Psychosis |
| Key points | The hyperlocomotion test can assess behavioral symptoms such as psychosis or mania in rats using an acute PCP-injection model. |
Abstract
Under- or overfeeding during pregnancy can lead to behavioral deficits in the offspring in later life. Here, we present a protocol for setting up and carrying out the hyperlocomotion test for assessing behavioral symptoms such as psychosis or mania. As an example, we use the acute rat phencyclidine-injection model which exhibits hyperlocomotion and stereotypic behaviors, resembling the positive symptoms of schizophrenia.
Citations in the library
Cited by 2
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