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“Eye Dropping”—A Case Report of Transconjunctival Lysergic Acid Diethylamide Drug Abuse

Danielle Lo, Lucy Cobbs, Michael Chua, Joshua Young, Ilyse D. Haberman, Yasha Modi

Cornea October 1, 2018 DOI: 10.1097/ico.0000000000001692 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Case report Peer reviewed
Sample size 1
Population 18-year-old man
Topics LSD
Citations 4
Key findings This is the first reported case of bilateral hemorrhagic conjunctival abrasion and corneal abrasion secondary to LSD administration via filter paper placed in the inferior conjunctival fornices.

Abstract

Purpose: To report a case of bilateral toxic corneal and conjunctival epitheliopathy secondary to administration of filter paper impregnated with lysergic acid diethylamide (LSD) in the inferior conjunctival fornices.

Methods: This is a single case report of an 18-year-old man who presented to the emergency department with acute, bilateral eye pain and redness of 24 hours. The patient admitted to placing folded strips of blotting paper impregnated with LSD into the inferior fornices of his eyes the previous night.

Results: The patient was found to have localized bilateral corneal and conjunctival abrasions with underlying subconjunctival hemorrhage. Conjunctival abrasion was “kissing,” involving the bulbar and palpebral conjunctiva, corresponding to the presumed location of the filter paper. There was no corneal stromal opacification. He was lost to follow up within 1 week of initial presentation but stated that his symptoms improved.

Conclusions: To the best of our knowledge, this is the first reported case of bilateral hemorrhagic conjunctival abrasion and corneal abrasion secondary to LSD. “Kissing” conjunctival lesions, which have been previously reported with heroin use, should raise suspicion for drug abuse.

Comparable studies

Other case reports and case series on LSD, most cited first.

Study Year Design Participants
Lasting Neuropsychiatric Sequelae of (??)Methylenedioxymethamphetamine (???Ecstasy???) in Recreational Users Persons who ingested large doses of MDMA 1991 Case study n = 2
Further Studies in the Therapeutic Value of Lysergic Acid Diethylamide in Mental Illness Patients with mental illness 1957 Case series
Coma, Hyperthermia, and Bleeding Associated with Massive LSD Overdose a Report of Eight Cases People who self-administered large amounts of pure LSD powder intranasally 1975 Case series n = 8
Using a MDMA- and LSD-Group Therapy Model in Clinical Practice in Switzerland and Highlighting the Treatment of Trauma-Related Disorders Patients with chronic complex post-traumatic stress disorder (c-PTSD), dissociative,... 2022 Case series
Persistent Palinopsia Following Ingestion of Lysergic Acid Diethylamide (LSD) Patients who developed persistent palinopsia after LSD ingestion 1996 Case series n = 3

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