An exploratory study of breathwork-induced altered states of consciousness in experienced practitioners: the airways to alteration (A2A) trial
Guy W. Fincham, Edward Caddye, Amy Kartar, Elizabeth A. Lilley, Nicola Stoke, Alessandro Colasanti
Frontiers in Psychology June 10, 2026 DOI: 10.3389/fpsyg.2026.1851882 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Preliminary experimental study Peer reviewed |
|---|---|
| Sample size | 24 |
| Population | Healthy adults |
| Interventions | High ventilation breathwork Body scan meditation |
| Duration | Single session, 1-week follow-up |
| Topics | Mysticism Altered states of consciousness Breathwork Philosophy of mind |
| Keywords | Exploratory research Context archaeology Altered state Consciousness Depression economics Nocebo Exploratory analysis Clinical psychology Psychotherapist Young adult Depressed mood Depressive symptoms |
| Key findings | Breathwork was associated with larger acute psychedelic-like effects, emotional breakthrough, and greater psychological insight and behavioral change at one-week follow-up compared to body scan meditation. |
Abstract
Background: Breathwork that increases ventilatory rate or depth represents an accessible non-pharmacological modality for potentially inducing altered states of consciousness (ASCs). Despite gaining traction as a potential therapeutic tool, empirical controlled research on breathwork and ASCs remains limited.
Methods: We examined the effects of a single session of high ventilation breathwork, compared to body scan meditation, in 24 healthy adults with primary outcomes of acute ASCs including mystical experience and emotional breakthrough. Sub-acute secondary outcomes were collected 1 week later.
Results: Breathwork was associated with larger effects on oceanic boundlessness ( p = 0.007, r = 0.63), visionary restructuralisation ( p = 0.018, r = 0.60), total mystical experience ( p = 0.007, r = 0.66), oneness ( p = 0.018, r = 0.60), positive mood ( p = 0.007, r = 0.66), ineffability ( p = 0.038, r = 0.55), and emotional breakthrough ( p = 0.028, r = 0.45). At follow-up, breathwork was associated with substantially greater psychological insight ( p = 0.002, r = 0.67) and behavioral change ( p = 0.008, r = 0.60) relative to body scan meditation. Stress, anxiety, depression and wellbeing improved in both groups over time.
Discussion: Results from this preliminary experimental study indicate that breathwork is associated with larger acute psychedelic-like effects than meditation, alongside greater emotional breakthrough, insight, and self-reported behavioral change. These exploratory relationships and preliminary observations provide greater context around breathwork-induced ASCs, and support the feasibility of ASC-focused breathwork research for future confirmatory trials.
Comparable studies
Other experimental studies on breathwork, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| Evaluation of the breathworks mindfulness‐based pain management programme: effects on well‐being and multiple measures of mindfulness Chronic pain patients | 2009 | Pilot investigation; quasi-experimental with intervention and comparison groups | |
| Neural Correlates of Non-ordinary States of Consciousness in Pranayama Practitioners: The Role of Slow Nasal Breathing Experienced meditators | 2022 | Within-subjects comparison | n = 12 |
| Measure of Significance of Holotropic Breathwork in the Development of Self-Awareness. Participants referred from Danish Holotropic Breathwork facilitators, including 9... | 2015 | Quasi-experiment with multiple case studies and repeated measures | n = 20 |
| An Effectiveness of Holotropic Breathwork on Stress Management among Higher Secondary Students in Selected Schools of Kanpur, Uttar Pradesh Higher secondary students at Sardar Patel Intermediate College, Mandhana, Kanpur, India | 2026 | Quasi-experimental study | n = 60 |
| A Study To Assess The Effectiveness Of Video Assisted Pranayama On Stress Among Students Of Selected College In Chennai College students at Saveetha College of Engineering, Chennai | 2026 | True experimental research design | n = 100 |
Citations in the library
Cites 27
- Psychometric Evaluation of the Altered States of Consciousness Rating Scale (OAV) PLoS One August 31, 2010
- Validation of the revised Mystical Experience Questionnaire in experimental sessions with psilocybin Journal of Psychopharmacology October 6, 2015
- The Standardized Psychometric Assessment of Altered States of Consciousness (ASCs) in Humans Pharmacopsychiatry July 1, 1998
- Mindfulness Meditation and Psychopathology Annual Review of Clinical Psychology December 11, 2018
- Emotional breakthrough and psychedelics: Validation of the Emotional Breakthrough Inventory. Journal of Psychopharmacology July 11, 2019
and 22 more in the library