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An exploratory study of breathwork-induced altered states of consciousness in experienced practitioners: the airways to alteration (A2A) trial

Guy W. Fincham, Edward Caddye, Amy Kartar, Elizabeth A. Lilley, Nicola Stoke, Alessandro Colasanti

Frontiers in Psychology June 10, 2026 DOI: 10.3389/fpsyg.2026.1851882 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Preliminary experimental study Peer reviewed
Sample size 24
Population Healthy adults
Interventions High ventilation breathwork Body scan meditation
Duration Single session, 1-week follow-up
Topics Mysticism Altered states of consciousness Breathwork Philosophy of mind
Keywords Exploratory research Context archaeology Altered state Consciousness Depression economics Nocebo Exploratory analysis Clinical psychology Psychotherapist Young adult Depressed mood Depressive symptoms
Key findings Breathwork was associated with larger acute psychedelic-like effects, emotional breakthrough, and greater psychological insight and behavioral change at one-week follow-up compared to body scan meditation.

Abstract

Background: Breathwork that increases ventilatory rate or depth represents an accessible non-pharmacological modality for potentially inducing altered states of consciousness (ASCs). Despite gaining traction as a potential therapeutic tool, empirical controlled research on breathwork and ASCs remains limited.

Methods: We examined the effects of a single session of high ventilation breathwork, compared to body scan meditation, in 24 healthy adults with primary outcomes of acute ASCs including mystical experience and emotional breakthrough. Sub-acute secondary outcomes were collected 1 week later.

Results: Breathwork was associated with larger effects on oceanic boundlessness ( p = 0.007, r = 0.63), visionary restructuralisation ( p = 0.018, r = 0.60), total mystical experience ( p = 0.007, r = 0.66), oneness ( p = 0.018, r = 0.60), positive mood ( p = 0.007, r = 0.66), ineffability ( p = 0.038, r = 0.55), and emotional breakthrough ( p = 0.028, r = 0.45). At follow-up, breathwork was associated with substantially greater psychological insight ( p = 0.002, r = 0.67) and behavioral change ( p = 0.008, r = 0.60) relative to body scan meditation. Stress, anxiety, depression and wellbeing improved in both groups over time.

Discussion: Results from this preliminary experimental study indicate that breathwork is associated with larger acute psychedelic-like effects than meditation, alongside greater emotional breakthrough, insight, and self-reported behavioral change. These exploratory relationships and preliminary observations provide greater context around breathwork-induced ASCs, and support the feasibility of ASC-focused breathwork research for future confirmatory trials.

Comparable studies

Other experimental studies on breathwork, most cited first.

Study Year Design Participants
Evaluation of the breathworks mindfulness‐based pain management programme: effects on well‐being and multiple measures of mindfulness Chronic pain patients 2009 Pilot investigation; quasi-experimental with intervention and comparison groups
Neural Correlates of Non-ordinary States of Consciousness in Pranayama Practitioners: The Role of Slow Nasal Breathing Experienced meditators 2022 Within-subjects comparison n = 12
Measure of Significance of Holotropic Breathwork in the Development of Self-Awareness. Participants referred from Danish Holotropic Breathwork facilitators, including 9... 2015 Quasi-experiment with multiple case studies and repeated measures n = 20
An Effectiveness of Holotropic Breathwork on Stress Management among Higher Secondary Students in Selected Schools of Kanpur, Uttar Pradesh Higher secondary students at Sardar Patel Intermediate College, Mandhana, Kanpur, India 2026 Quasi-experimental study n = 60
A Study To Assess The Effectiveness Of Video Assisted Pranayama On Stress Among Students Of Selected College In Chennai College students at Saveetha College of Engineering, Chennai 2026 True experimental research design n = 100

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