Pharmacokinetic parameters of mescaline in rabbits
C. Van Peteghem, A. Heyndrickx, W. Van Zele
European Journal of Drug Metabolism and Pharmacokinetics January 1, 1982 DOI: 10.1007/bf03189535 (opens in new tab) via OpenAlex
Summary
AI-generated from the abstractMescaline in rabbit plasma follows a two-compartment open model after intravenous injection. Half-life times for the alpha and beta phases, velocity constants, and steady-state distribution volumes are reported for four subjects, measured using a highly specific and sensitive mass fragmentographic method.
Study at a glance
| Characteristics | Pharmacokinetic study Peer reviewed |
|---|---|
| Sample size | 4 |
| Population | Rabbits |
| Intervention | Mescaline |
| Topics | Mescaline |
| Keywords | Pharmacokinetics Steady state chemistry Distribution mathematics Human physiology |
| Citations | 3 |
| Key finding | Mescaline pharmacokinetics in rabbits conforms to a two-compartment open model. |
Abstract
By means of a highly specific and sensitive mass fragmentographic method mescaline was measured in rabbit plasma samples, taken at various points after an i.v. injection. The pharmacokinetic behaviour conformed to the two-compartment open model. Half-life times of alpha and beta phases, velocity constants and steady-state distribution volumes of four subjects are reported.