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Hapten-immunological studies on mescaline

R. Utzinger

Psychopharmacology 1975 DOI: 10.1007/bf00428941 (opens in new tab)

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Study at a glance

AI-extracted from the abstract
Characteristics Experimental study Peer reviewed
Population Rabbits and rats
Intervention 4
Topics Mescaline
Keywords Hapten Immunization Antibody Conjugate Immunology Pharmacology Drug-induced adverse reactions
Citations 3
Key findings Immunization with mescaline conjugates raised antibodies that bound mescaline and altered behavioral responses to the drug in rats.

Abstract

Antibodies with mescaline binding specificity were raised in rabbits by immunization with conjugates of bovine serum albumin with mescaline or its analogue 3,4,5-trimethoxyphenylacetic acid. Immunized rats were given mescaline and their behavior was compared to that of non-immunized controls.

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