Hapten-immunological studies on mescaline
Psychopharmacology January 1, 1975 DOI: 10.1007/bf00428941 (opens in new tab) via OpenAlex
Summary
AI-generated from the abstractRabbits produced antibodies that specifically bind mescaline after being immunized with conjugates of bovine serum albumin and mescaline or its analogue 3,4,5-trimethoxyphenylacetic acid. Immunized rats that received mescaline showed behavioral differences compared to non-immunized controls, suggesting that the antibodies altered the drug's effects.
Study at a glance
| Characteristics | Experimental study Peer reviewed |
|---|---|
| Population | Rabbits and rats |
| Intervention | 4 |
| Topics | Mescaline |
| Keywords | Hapten Immunization Antibody Conjugate |
| Citations | 3 |
| Key finding | Immunization with mescaline conjugates raised antibodies that bound mescaline and altered behavioral responses to the drug in rats. |
Abstract
Antibodies with mescaline binding specificity were raised in rabbits by immunization with conjugates of bovine serum albumin with mescaline or its analogue 3,4,5-trimethoxyphenylacetic acid. Immunized rats were given mescaline and their behavior was compared to that of non-immunized controls.