Mescaline, 3,4-Dimethoxyphenylethylamine, and Adrenaline: Sites of Electroencephalographic Arousal
Science December 3, 1965 DOI: 10.1126/science.150.3701.1309 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Experimental study Peer reviewed |
|---|---|
| Population | Rabbit brain |
| Interventions | Adrenaline mescaline 3 4-dimethoxyphenylethylamine |
| Topics | Mescaline |
| Keywords | Arousal Midbrain Brainstem Electroencephalography Anesthesia |
| Citations | 25 |
| Key findings | Adrenaline produces electroencephalographic arousal at the midbrain level, while mescaline and 3,4-dimethoxyphenylethylamine produce arousal at the medullary level of the brainstem. |
Abstract
Transections of the brain of rabbit reveal that electroencephalographic arousal produced by injections of adrenaline takes place at the midbrain level, while mescaline and 3,4-dimethoxyphenylethylamine induce such arousal lower in the brainstem, at the medullary level.
Comparable studies
Other experimental studies on mescaline, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| Enzymatic Formation of Psychotomimetic Metabolites from Normally Occurring Compounds Rabbit lung | 1961 | Experimental study | |
| PSYCHOTOMIMETICS, CLINICAL AND THEORETICAL CONSIDERATIONS: HARMINE, WIN-2299 AND NALLINE Schizophrenic patients | 1957 | Experimental study | |
| Phencyclidine, Lysergic Acid Diethylamide, and Mescaline: Cerebral Artery Spasms and Hallucinogenic Activity Isolated basilar and middle cerebral arteries | 1981 | Experimental study | |
| Acquired and Crossed Tolerance to Mescaline, LSD-25, and BOL-148 | 1959 | Experimental study | |
| Effects of Hallucinogenic and Tranquilizing Drugs on Serotonin Evoked Uterine Contractions. Uterus of spayed rat | 1956 | Experimental study |
Citations in the library
Cited by 3
- Mescaline and Related Compounds Birkhäuser Basel eBooks 1968
- Cross tolerance to antinociception elicited by intracerebroventricular administration of mescaline and morphine to rabbits, and EEG correlates Psychopharmacology 1976
- Mammalian Biosynthesis of Potential Psychotogens Derived from Dopamine Catecholamines and Behavior · 1 1975