Memory impairment in now abstinent MDMA users and continued users: A longitudinal follow-up
Konstantine K. Zakzanis, Zachariah Campbell
Neurology March 13, 2006 DOI: 10.1212/01.wnl.0000200957.97779.ea (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Observational cohort Longitudinal Peer reviewed |
|---|---|
| Sample size | 15 |
| Population | Participants with a history of MDMA use |
| Duration | 2-year follow-up |
| Topics | MDMA |
| Keywords | Neuropsychology Neuropsychological test Memory impairment Neurotoxicity Clinical psychology Audiology Cognition |
| Citations | 54 |
| Key findings | Current MDMA users showed further declines in memory ability over two years, while former users improved or remained static on memory measures. |
Abstract
The authors further investigated the functional consequences of continued neurotoxicity of (+/-)3,4-methylenedioxymethamphetamine (MDMA) use. Fifteen participants who were previously given a brief neuropsychological battery were tested for a third time 2 years after baseline. At 2 years, seven participants were still using MDMA, whereas eight participants had become abstinent from MDMA since 1-year testing. Current users demonstrated further declines in memory ability; former users improved on several memory measures or remained static in performance.