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Memory impairment in abstinent MDMA (“Ecstasy”) users: A longitudinal investigation

Konstantine K. Zakzanis, Donald A. Young

Neurology April 10, 2001 DOI: 10.1212/wnl.56.7.966 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Longitudinal study Peer reviewed
Sample size 15
Population MDMA users
Duration 1 year
Topics MDMA
Keywords Neuropsychology Recall Retrospective memory Neuropsychological test Longitudinal study Clinical psychology Episodic memory
Citations 122
Key findings Continued use of MDMA was associated with progressive decline in immediate and delayed recall.

Abstract

To examine the neurotoxic potential of continued MDMA ("Ecstasy") use in humans and its functional consequences over the course of 1 year, 15 MDMA users participated in a longitudinal study in which they completed a brief neuropsychological test battery composed mainly of retrospective and prospective memory tasks. Subjects were abstinent for 2 weeks on initial and 1-year testing. Continued use of MDMA was associated with progressive decline in terms of immediate and delayed recall.

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