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LSD Flashbacks

Johanna A. Hoffman

Archives of General Psychiatry June 1, 1984 DOI: 10.1001/archpsyc.1984.01790170105015 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Case study Case report Peer reviewed
Sample size 1
Population A woman with visual symptoms but no history of LSD ingestion
Interventions thiothixene trifluoperazine hydrochloride
Duration Short trials
Topics LSD
Keywords Afterimage Confusion Hallucinogen Ingestion Psychoanalysis
Citations 7
Key findings A patient without hallucinogen exposure reported 14 of 16 visual symptoms typical of LSD flashbacks, and neuroleptics worsened her symptoms.

Abstract

To the Editor.— I read with interest Abraham's article on "Visual Phenomenology of the LSD Flashback."1The description of visual flashbacks and the apparent reduction in symptoms with the administration of a benzodiazepine called to mind the case of a woman I treated whose major difference from the patients in Abraham's group was the absence of a history of LSD ingestion. This patient had experienced the onset of visual symptoms at the age of 17 years during a near-psychotic upheaval, without any known exposure to hallucinogens. Of the 16 visual symptoms described by Abraham, my patient reported 14. Of the remaining two, she did not spontaneously endorse color confusion or positive afterimages but did not deny them. These visual distortions had persisted during the 20 years since their onset, although with decreased frequency. During short trials of two neuroleptics (thiothixene and trifluoperazine hydrochloride), she reported an increase in

Comparable studies

Other case reports and case series on LSD, most cited first.

Study Year Design Participants
Lasting Neuropsychiatric Sequelae of (??)Methylenedioxymethamphetamine (???Ecstasy???) in Recreational Users Persons who ingested large doses of MDMA 1991 Case study n = 2
Further Studies in the Therapeutic Value of Lysergic Acid Diethylamide in Mental Illness Patients with mental illness 1957 Case series
Coma, Hyperthermia, and Bleeding Associated with Massive LSD Overdose a Report of Eight Cases People who self-administered large amounts of pure LSD powder intranasally 1975 Case series n = 8
Using a MDMA- and LSD-Group Therapy Model in Clinical Practice in Switzerland and Highlighting the Treatment of Trauma-Related Disorders Patients with chronic complex post-traumatic stress disorder (c-PTSD), dissociative,... 2022 Case series
Persistent Palinopsia Following Ingestion of Lysergic Acid Diethylamide (LSD) Patients who developed persistent palinopsia after LSD ingestion 1996 Case series n = 3

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