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Multiple Ocular Anomalies Associated With Maternal LSD Ingestion

Calvin Chun-Kit Chan, M. Fishman, P. R. Egbert

Archives of Ophthalmology February 1, 1978 DOI: 10.1001/archopht.1978.03910050150009 (opens in new tab)

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Study at a glance

AI-extracted from the abstract
Characteristics Case study Case report Peer reviewed
Sample size 1
Population Premature baby girl
Topics LSD
Keywords Microphthalmos Pregnancy Ingestion Teratology Ophthalmology Gestation
Citations 46
Key findings Severe ocular malformations occurred in a premature infant whose mother ingested LSD during the first trimester, representing the third reported case of possible LSD-related eye teratogenesis.

Abstract

Severe ocular malformations, including microphthalmos, intraocular cartilage, cataract, persistent hyperplastic primary vitreous, and retinal dysplasia, occurred in a premature baby girl. The mother had ingested LSD during the first trimester of pregnancy. To our knowledge, this is the third case reported of ocular teratogenesis associated with maternal LSD ingestion. Further cases must be documented to establish an actual cause and effect relationship between the drug and the induced malformations.

Comparable studies

Other case reports and case series on LSD, most cited first.

Study Year Design Participants
Lasting Neuropsychiatric Sequelae of (??)Methylenedioxymethamphetamine (???Ecstasy???) in Recreational Users Persons who ingested large doses of MDMA 1991 Case study n = 2
Further Studies in the Therapeutic Value of Lysergic Acid Diethylamide in Mental Illness Patients with mental illness 1957 Case series
Coma, Hyperthermia, and Bleeding Associated with Massive LSD Overdose a Report of Eight Cases People who self-administered large amounts of pure LSD powder intranasally 1975 Case series n = 8
Using a MDMA- and LSD-Group Therapy Model in Clinical Practice in Switzerland and Highlighting the Treatment of Trauma-Related Disorders Patients with chronic complex post-traumatic stress disorder (c-PTSD), dissociative,... 2022 Case series
Persistent Palinopsia Following Ingestion of Lysergic Acid Diethylamide (LSD) Patients who developed persistent palinopsia after LSD ingestion 1996 Case series n = 3

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