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Multiple Ocular Anomalies Associated With Maternal LSD Ingestion

Calvin Chun-Kit Chan, M. Fishman, P. R. Egbert

Archives of Ophthalmology February 1, 1978 DOI: 10.1001/archopht.1978.03910050150009 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Case study Case report Peer reviewed
Sample size 1
Population Premature baby girl
Topics LSD
Keywords Microphthalmos Pregnancy Ingestion Teratology Ophthalmology Gestation
Citations 46
Key findings Severe ocular malformations occurred in a premature infant whose mother ingested LSD during the first trimester, representing the third reported case of possible LSD-related eye teratogenesis.

Abstract

Severe ocular malformations, including microphthalmos, intraocular cartilage, cataract, persistent hyperplastic primary vitreous, and retinal dysplasia, occurred in a premature baby girl. The mother had ingested LSD during the first trimester of pregnancy. To our knowledge, this is the third case reported of ocular teratogenesis associated with maternal LSD ingestion. Further cases must be documented to establish an actual cause and effect relationship between the drug and the induced malformations.