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Quantitative analysis of psilocybin and psilocin and psilocybe baecystis (singer and smith) by high-performance liquid chromatography and by thin-layer chromatography

Michael Beug, Jeremy Bigwood

Journal of Chromatography A March 1, 1981 DOI: 10.1016/s0021-9673(00)88741-5 (opens in new tab) via OpenAlex

Summary

AI-generated from the abstract

A method for rapidly measuring the amounts of psilocybin and psilocin in wild mushroom extracts uses reversed-phase high-performance liquid chromatography with paired-ion reagents. Nine solvent systems and three solid supports were tested for how well they separate psilocybin, psilocin, and other components of crude mushroom extracts using thin-layer chromatography.

Study at a glance

Characteristics Method development and evaluation Peer reviewed
Topics Psilocybin
Keywords Chemistry Thin-layer chromatography High-performance liquid chromatography Reagent
Citations 52
Key finding Reversed-phase high-performance liquid chromatography with paired-ion reagents enables rapid quantification of psilocybin and psilocin in wild mushroom extracts.

Abstract

Rapid quantification of psilocybin and psilocin in extracts of wild mushrooms is accomplished by reversed-phase high-performance liquid chromatography with paired-ion reagents. Nine solvent systems and three solid supports are evaluated for their efficiency in separating psilocybin, psilocin and other components of crude mushroom extracts by thin-layer chromatography.

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