The Quantitation of Psilocybin in Hallucinogenic Mushrooms Using High Performance Liquid Chromatography
Journal of Forensic Sciences October 1, 1983 DOI: 10.1520/jfs11601j (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Method development Peer reviewed |
|---|---|
| Topics | Psilocybin |
| Keywords | High-performance liquid chromatography Phosphoric acid Hallucinogen Solid phase extraction Extraction chemistry Organic chemistry Pharmacology |
| Citations | 21 |
| Key points | A rapid, selective, and accurate HPLC method with a one-step extraction was developed for quantitating psilocybin in dry mushroom material. |
Abstract
Abstract A method using high performance liquid chromatography (HPLC) with an acetonitrile, water, and phosphoric acid mobile phase and a bonded cyano-amino-type polar phase column has been developed for the rapid, selective, and accurate quantitation of psilocybin in dry mushroom material. A simple one-step procedure is used for the quantitative extraction of psilocybin in under 60 min. The 267:254 nm absorbance ratio is used as a check on peak purity for the psilocybin response.
Citations in the library
Cited by 10
- Morphological and chemical analysis of magic mushrooms in Japan. Forensic Science International December 17, 2003
- Fungal Hallucinogens Psilocin, Ibotenic Acid, and Muscimol Therapeutic Drug Monitoring July 12, 2013
- Extraction and analysis of indole derivatives from fungal biomass Journal of Basic Microbiology 1994
- Analysis of psilocybin and psilocin in Psilocybe subcubensis GUZMÁN by ion mobility spectrometry and gas chromatography–mass spectrometry Forensic Science International 1999
- The Determination of Psilocin and Psilocybin in Hallucinogenic Mushrooms by HPLC Utilizing a Dual Reagent Acidic Potassium Permanganate and Tris(2,2′‐bipyridyl)ruthenium(II) Chemiluminescence Detection System Journal of Forensic Sciences 2006
and 5 more in the library
Cites 4
- Quantitative analysis of psilocybin and psilocin and psilocybe baecystis (singer and smith) by high-performance liquid chromatography and by thin-layer chromatography Journal of Chromatography A March 1, 1981
- GLC-Mass Spectral Analysis of Psilocin and Psilocybin Journal of Pharmaceutical Sciences May 1, 1977
- Analysis of Psilocybin and Psilocin in Mushroom Extracts by Reversed-Phase High Performance Liquid Chromatography Journal of Forensic Sciences October 1, 1980
- The Content of Psilocybin in Norwegian Psilocybe semilanceata Planta Medica July 1, 1981