The transformational power of psychedelics: catalysts for creativity, consciousness, and mental health.
Xiubo Du, Jiantao Liu, Xiaohui Wang
Molecular Psychiatry September 30, 2025 DOI: 10.1038/s41380-025-03291-8 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Theoretical or philosophical paper Peer reviewed |
|---|---|
| Citations | 2 |
| Key points | Proposes that psychedelics can catalyze creative and transformative modes of thinking by integrating neurobiological, clinical, and cultural insights. |
Abstract
Psychedelics, such as psilocybin, lysergic acid diethylamide (LSD), ketamine, and N,N-dimethyltryptamine (DMT), have captured the attention of scientists, artists, and seekers alike for their profound ability to alter consciousness and inspire creativity. The concept of "creation" encompasses multiple interpretations-ranging from generating novel ideas to fostering personal transformation. This perspective explores how psychedelics interact with the concept of creation, examining their role in enhancing artistic inspiration, facilitating spiritual experiences, and driving therapeutic breakthroughs in mental health treatment. By integrating findings from neurobiological research, clinical applications, and cultural analysis, we offer a holistic view of how psychedelics may catalyze innovative modes of thinking and awaken the mind's creative and transformative potential. As these substances gain prominence as tools for reshaping our understanding of consciousness and psychological healing, their broader integration into society requires careful consideration of legal complexities, ethical responsibilities, and cultural contexts to ensure their use is evidence-based, respectful, and responsibly guided.
Citations in the library
Cited by 3
- Inaugural year of regulated psilocybin services in Oregon: safety, motivations, and utilization Frontiers in Psychiatry May 13, 2026
- Chemical ecology and convergent evolution of natural hallucinogens: From ecological defense to conserved neural targets Proceedings of the National Academy of Sciences June 24, 2026
- Psychedelics and astrocytes: a hypothesis-driven perspective on neuro-glial integration, network plasticity, and neuroimmune reprogramming. Molecular Psychiatry August 11, 2026
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