Mechanisms of sustained mindfulness practice in stroke survivors: A critical realist secondary analysis of the HEADS: UP intervention.
Naomi E. Clark, Ben Parkinson, Xu Wang, Bridget Davis, Lisa Kidd, Maggie Lawrence
Complementary Therapies in Clinical Practice December 23, 2025 DOI: 10.1016/j.ctcp.2025.102041 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Secondary analysis of qualitative data from a randomized controlled trial Peer reviewed |
|---|---|
| Sample size | 12 |
| Population | Stroke survivors who completed the HEADS: UP mindfulness-based intervention |
| Duration | 6-month follow-up |
| Topics | Anxiety Depression Meditation |
| Keywords | Maintenance Secondary data analysis Stroke |
| Key findings | Seven mechanisms—including believing in benefits, personal preferences, continued learning, social attitudes, togetherness, structured practice, and competing priorities—determined whether stroke survivors sustained mindfulness practice after completing the HEADS: UP intervention. |
Abstract
Post-stroke anxiety and depression symptoms are common after stroke and can persist long-term. Despite this, there is a lack of long-term psychological support for post-stroke anxiety and depression. Mindfulness-based interventions are emerging as feasible, acceptable and potentially effective interventions for post-stroke anxiety and depression. Sustained use of mindfulness practice can help stroke survivors to self-manage their anxiety and depression in the long-term. However, stroke survivors' experiences of continued practice following a mindfulness-based intervention have yet to be explored. This study aims to identify mechanisms underpinning sustained mindfulness practice by stroke survivors following completion of an adapted, stroke-specific mindfulness-based intervention called HEADS: UP (Helping Ease Anxiety and Depression After Stroke). A secondary analysis of 6-month follow-up qualitative data from course participants (n = 12) in the HEADS: UP randomised controlled trial was analysed using critical realist thematic analysis. Seven mechanisms were identified as determining sustained mindfulness practice: 1) Believing continued practice brings benefits, 2) Personal preferences and accessibility, 3) Continued learning, 4) Attitudes of others and society, 5) Togetherness and connection, 6) Structuring and scaffolding practice, and 7) Competing priorities. The mechanisms provide explanations behind stroke survivors' experiences of sustained mindfulness practice following HEADS: UP. The findings highlighted the potential benefit of providing support following a mindfulness-based intervention to facilitate sustained practice. Awareness of the mechanisms could aid future intervention design and help clinical practitioners and stroke support professionals support continued mindfulness practice.
Comparable studies
Other randomized controlled trials on meditation, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| Alterations in Brain and Immune Function Produced by Mindfulness Meditation Healthy employees in a work environment | 2003 | Randomized controlled trial | n = 41 |
| Prevention of relapse/recurrence in major depression by mindfulness-based cognitive therapy. Recovered recurrently depressed patients | 2000 | Randomized controlled trial | n = 145 |
| Open hearts build lives: Positive emotions, induced through loving-kindness meditation, build consequential personal resources. Working adults | 2008 | Randomized controlled trial | n = 139 |
| Short-term meditation training improves attention and self-regulation Undergraduate Chinese students | 2007 | Randomized controlled trial | n = 40 |
| Mindfulness-Based Cognitive Therapy for Depression: Replication and Exploration of Differential Relapse Prevention Effects. Recovered recurrently depressed patients | 2004 | Randomized controlled trial | n = 73 |
Citations in the library
Cites 18
- What defines mindfulness-based programs? The warp and the weft Psychological Medicine December 29, 2016
- Mindfulness-based interventions: an overall review British Medical Bulletin April 21, 2021
- Four-Year Follow-Up of a Meditation-Based Program for the Self-Regulation of Chronic Pain Clinical Journal of Pain 1986
- Mindfulness and self-compassion as predictors of psychological wellbeing in long-term meditators and matched nonmeditators The Journal of Positive Psychology April 11, 2012
- An Exploration of Formal and Informal Mindfulness Practice and Associations with Wellbeing Mindfulness May 21, 2018
and 13 more in the library