Correction: Synergistic, multi-level understanding of psychedelics: three systematic reviews and meta-analyses of their pharmacology, neuroimaging and phenomenology.
Kenneth Shinozuka, Katarina Jerotic, Pedro A. M. Mediano, Alex T. Zhao, Katrin H. Preller, Robin Carhart-Harris, Morten L. Kringelbach
Translational Psychiatry November 13, 2025 correction DOI: 10.1038/s41398-025-03731-7 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Meta-analysis correction |
|---|---|
| Measures | 11-dimensional Altered States of Consciousness (11D-ASC), 5D-ASC |
| Topics | Philosophy of mind |
| Keywords | Psychedelics Brain activity Consciousness Mental well-being |
| Key findings | After removing three studies with duplicated data from the 11D-ASC meta-analysis, the authors report results generally similar to the original findings: of 33 LSD-versus-psilocybin comparisons, insightfulness at medium dose became non-significant and disembodiment at medium dose became more significant. The 5D-ASC meta-analysis, which contained no duplicates, is unaffected. |
Abstract
The meta-analysis of the 11-dimensional Altered States of Consciousness (11D-ASC) included three studies that contained duplicated data from other papers: Duerler et al. (2021), Lewis et al. (2017), and Preller et al. (2017). When these studies are removed from the analysis, the results are generally similar to the previously reported findings. Out of 33 comparisons (3 doses x 11 dimensions) between LSD and psilocybin, one becomes insignificant (insightfulness, medium dose), while one becomes more significant (disembodiment, medium dose). Note that the 5D-ASC meta-analysis did not include any duplicates, hence the results of that meta-analysis are unaffected.
Comparable studies
Other systematic reviews and meta-analyses on philosophy of mind, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| The brain in flow: A systematic review on the neural basis of the flow state. Participants in studies measuring or manipulating flow state with brain activity recording | 2022 | Systematic review | n = 471 |
| Synergistic, multi-level understanding of psychedelics: three systematic reviews and meta-analyses of their pharmacology, neuroimaging and phenomenology. | 2024 | Systematic review and meta-analysis | |
| Evidence synthesis indicates contentless experiences in meditation are neither truly contentless nor identical Expert texts from Shamatha, Transcendental, and Stillness Meditation traditions | 2022 | Systematic review | n = 135 |
| Novel psychoactive substances (NPS) use in severe mental illness (SMI) patients: Potential changes in the phenomenology of psychiatric diseases Patients with severe mental illness (SMI), such as psychotic patients | 2017 | Systematic review | |
| Scoping review on shamanistic trances practices. | 2024 | Systematic review |