Combined Mindfulness-Based Stress Reduction and Exercise Intervention for Improving Psychological Well-Being in Patients With Non-Small Cell Lung Cancer.
Yan-Li Wang, Xiao-Fang Zhang, Xiao-Ping Wang, Ya-Jing Zhang, Yuan-Yuan Jin, Wan-Ling Li
Clinical Psychology & Psychotherapy 2024 DOI: 10.1002/cpp.3023 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Randomized controlled trial Peer reviewed |
|---|---|
| Sample size | 60 |
| Population | Patients with non-small cell lung cancer (NSCLC) who had not received surgical treatment |
| Interventions | Mindfulness-based stress reduction Exercise therapy |
| Duration | 8-week intervention, with assessments at 6 and 8 weeks |
| Topics | Anxiety Depression Meditation |
| Keywords | Exercise intervention Insomnia Lung cancer Mindfulness‐based stress reduction |
| Citations | 16 |
| Key findings | The combination of mindfulness-based stress reduction and exercise intervention significantly improved anxiety, depression, sleep quality, and overall psychological distress in patients with non-small cell lung cancer compared to conventional psychological nursing care. |
Abstract
This study aims to assess the clinical effectiveness of combining mindfulness-based stress reduction (MBSR) with exercise intervention in improving anxiety, depression, sleep quality and mood regulation in patients with non-small cell lung cancer (NSCLC). A total of 60 patients with NSCLC who had not received surgical treatment were selected using convenience sampling and divided into an intervention group and control group, with 30 patients in each group. The control group received conventional psychological nursing care, whereas the intervention group received a combination of MBwSR and exercise therapy. Before the intervention, a questionnaire was completed to collect the basic data of the two groups. Further questionnaires were administered at 6 and 8 weeks after treatment to assess anxiety, depression, sleep quality and other items included in the five-item Brief Symptom Rating Scale (BSRS-5). No significant differences between the intervention and control groups were identified in terms of personal and clinical characteristics (p > 0.05). No significant differences were determined in the BSRS-5, Self-Rating Anxiety Scale (SAS), Self-Rating Depression Scale (SDS) or Pittsburgh Sleep Quality Index (PSQI) scores between the intervention and control groups before the intervention. However, 6 and 8 weeks after the intervention, scores were significantly lower in both groups (p < 0.001). Significant differences in the BSRS-5, SAS, SDS and PSQI scores were identified between the two groups at different time points (p < 0.001). The combination of MBSR and exercise intervention demonstrated improvements in anxiety, depression, sleep quality and BSRS-5 scores in patients with NSCLC.
Comparable studies
Other randomized controlled trials on meditation, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| Alterations in Brain and Immune Function Produced by Mindfulness Meditation Healthy employees in a work environment | 2003 | Randomized controlled trial | n = 41 |
| Prevention of relapse/recurrence in major depression by mindfulness-based cognitive therapy. Recovered recurrently depressed patients | 2000 | Randomized controlled trial | n = 145 |
| Open hearts build lives: Positive emotions, induced through loving-kindness meditation, build consequential personal resources. Working adults | 2008 | Randomized controlled trial | n = 139 |
| Short-term meditation training improves attention and self-regulation Undergraduate Chinese students | 2007 | Randomized controlled trial | n = 40 |
| Mindfulness-Based Cognitive Therapy for Depression: Replication and Exploration of Differential Relapse Prevention Effects. Recovered recurrently depressed patients | 2004 | Randomized controlled trial | n = 73 |
Citations in the library
Cited by 4
- Effects of mindfulness-based interventions (MBIs) on quality of sleep among patients with cancer: A systematic review and meta-analysis of randomized controlled trials. Journal of Psychosomatic Research May 1, 2025
- The Combined Effect of Mindfulness and Physical Activity on Stress: A Systematic Review and Meta-Analysis of Randomized Controlled Trials Behavioral Sciences September 11, 2026
- Intervention effects of subconscious cultivation in mindfulness-based physical education teaching and training on pain perception and psychological resilience in advanced cancer patients Psycho-Oncologie December 17, 2025
- Mindfulness-Based Interventions for Depression, Anxiety, and Stress in Adults With Cancer: A Stratified Subgroup Meta-Analysis. Psycho-Oncology March 1, 2026
Cites 8
- Effects of Mindfulness Training and Exercise on Cognitive Function in Older Adults: A Randomized Clinical Trial. JAMA December 13, 2022
- Mindfulness-based stress reduction may decrease stress, disease activity, and inflammatory cytokine levels in patients with autoimmune hepatitis. JHEP reports : innovation in hepatology May 2022
- The mindfulness-based stress reduction program for improving sleep quality in cancer survivors: A systematic review and meta-analysis. Complementary Therapies in Medicine January 15, 2021
- The Effect of Mindfulness-Based Training on Stress, Anxiety, Depression, and Job Satisfaction Among Ward Nurses: A Randomized Control Trial. Journal of Nursing Management May 20, 2020
- Mindfulness-based Cognitive Therapy for Psychological Distress, Fear of Cancer Recurrence, Fatigue, Spiritual Wellbeing and Quality of Life in Patients with Breast Cancer - a Randomized Control Trial. Journal of Pain and Symptom Management February 24, 2020
and 3 more in the library