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Intervention effects of subconscious cultivation in mindfulness-based physical education teaching and training on pain perception and psychological resilience in advanced cancer patients

Zuo Tian, Hong Zhang, Shengxian Chen

Psycho-Oncologie December 17, 2025 DOI: 10.18282/po4670 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Randomized controlled trial Double-blind Peer reviewed
Sample size 128
Population Late-stage cancer patients
Interventions Mindfulness-based physical education training Subconscious cultivation techniques
Duration 8 weeks, with baseline, postintervention, and follow-up assessments
Measures Brief Pain Inventory, Resilience Scale for Adults, Five Facet Mindfulness Questionnaire, Subconscious Awareness Scale, EEG biofeedback
Topics Meditation
Key findings Mindfulness-based physical education training combined with subconscious cultivation techniques reduced pain intensity by 26.3% and pain interference by 32.5% and increased psychological resilience by 25.1% in late-stage cancer patients, with control-group improvements under 8%. The authors report that subconscious state improvement mediated the resilience enhancement, accounting for 48.7% of the total effect.

Abstract

To explore the intervention effects and psychological mechanisms of subconscious cultivation in mindfulness-based physical education training on pain perception and psychological resilience in late-stage cancer patients.

Methods: A double-blind randomized controlled trial design was adopted, with 128 late-stage cancer patients randomly allocated to intervention and control groups at a 1:1 ratio. The intervention group received 8 weeks of mindfulness-based physical education training combined with subconscious cultivation techniques, while the control group received routine health education and general physical activities. The Brief Pain Inventory, Resilience Scale for Adults, Five Facet Mindfulness Questionnaire, Subconscious Awareness Scale, and EEG biofeedback technology were used to assess intervention effects. Data collection included three time points: baseline, postintervention, and follow-up.

Results: The intervention group’s pain intensity scores decreased from baseline 6.42 ± 1.58 to 4.73 ± 1.42, an improvement of 26.3% (p < 0.001); pain interference scores improved by 32.5% (p < 0.001). Psychological resilience total scores increased from 98.35 ± 18.26 to 124.67 ± 19.85, an improvement of 25.1% (p < 0.001), with all dimensions showing improvements exceeding 20%. EEG monitoring showed α-wave power density increased by 68.4% and θ-wave power density increased by 66.2% (both p < 0.001). Mediation analysis indicated that subconscious state improvement played a significant mediating role between the intervention program and psychological resilience enhancement (mediation effect = 0.423, accounting for 48.7% of the total effect). Pain catastrophizing decreased by 33.4%, pain acceptance increased by 50.8%, and cognitive reappraisal ability improved by 32.1% (all p < 0.001). Total emotion regulation difficulties improved by 33.2%, and 87.5% of patients reported being able to spontaneously initiate mindful coping strategies. The control group showed improvements of less than 8% across all indicators. Intervention effects remained stable during the follow-up period.

Conclusion: Mindfulness-based physical education training combined with subconscious cultivation techniques can significantly improve pain perception and psychological resilience levels in late-stage cancer patients. Subconscious cultivation plays an important mediating role in psychological resilience enhancement, with subconscious regulation of cognitive reappraisal ability and subconscious integration of emotion regulation strategies being key psychological mechanisms. This intervention model provides new theoretical basis and practical solutions for psychological rehabilitation of cancer patients.

Comparable studies

Other randomized controlled trials on meditation, most cited first.

Study Year Design Participants
Alterations in Brain and Immune Function Produced by Mindfulness Meditation Healthy employees in a work environment 2003 Randomized controlled trial n = 41
Prevention of relapse/recurrence in major depression by mindfulness-based cognitive therapy. Recovered recurrently depressed patients 2000 Randomized controlled trial n = 145
Open hearts build lives: Positive emotions, induced through loving-kindness meditation, build consequential personal resources. Working adults 2008 Randomized controlled trial n = 139
Short-term meditation training improves attention and self-regulation Undergraduate Chinese students 2007 Randomized controlled trial n = 40
Mindfulness-Based Cognitive Therapy for Depression: Replication and Exploration of Differential Relapse Prevention Effects. Recovered recurrently depressed patients 2004 Randomized controlled trial n = 73

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