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Neo-clerodane diterpenes from the hallucinogenic sage Salvia divinorum.

Osamu Shirota, Kumi Nagamatsu, Setsuko Sekita

Journal of Natural Products December 1, 2006 DOI: 10.1021/np060456f (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Phytochemical study Peer reviewed
Population Salvia divinorum plant material
Topics Salvia divinorum
Keywords Salvia divinorum chemistry Salvia divinorum compounds Salvia divinorum phytochemistry Salvia divinorum constituents Neo-clerodane diterpenes Salvidivins Salvinorins Divinatorin Natural product discovery Compound identification Chemical characterization Novel compounds Phytochemical research Plant chemistry
Citations 68
Key points Seven new neo-clerodane diterpenes were isolated and structurally characterized from Salvia divinorum.

Abstract

Seven new neo-clerodane diterpenes, salvidivins A (2), B, (3), C (4), and D (5), salvinorins H (6) and I (7), and divinatorin [corrected] F (8), along with eight known neo-clerodane diterpenes, salvinorins A (1)-F, divinatorins A and B, and seven other constituents, were isolated from the hallucinogenic sage Salvia divinorum. The structures of 1-7 were elucidated on the basis of 2D NMR spectroscopic studies.