Salvinorin C, a new neoclerodane diterpene from a bioactive fraction of the hallucinogenic Mexican mint Salvia divinorum.
Leander J. Valdés, H M Chang, Daniel C. Visger, Masato Koreeda
Organic Letters November 29, 2001 DOI: 10.1021/ol016820d (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Natural product isolation and structural elucidation Peer reviewed |
|---|---|
| Topics | Salvia divinorum |
| Keywords | Phytochemistry Plant chemistry Natural products chemistry Botanical chemistry Natural compounds Bioactive compounds Plant metabolites Spectroscopy Spectrometry Analytical chemistry Structural elucidation Mexican mint Psychoactive plants Medicinal plants |
| Citations | 81 |
| Key points | Salvinorin C was isolated from Salvia divinorum and its structure was elucidated using NMR spectroscopy and comparison with derivatives. |
Abstract
Salvinorin C (1), a minor component from a biologically active TLC fraction, was isolated from the leaves of the Mexican mint Salvia divinorum. Its structure was elucidated on the basis of extensive proton and C-13 NMR experiments, as well as by comparison of the NMR data with those of the mono- and diacetate derivatives 5-7 of the major NaBH(4)-reduction product of salvinorin A (2). [structure: see text]
Citations in the library
Cited by 44
- Salvinorin A: a potent naturally occurring nonnitrogenous kappa opioid selective agonist. Proceedings of the National Academy of Sciences September 3, 2002
- Dose-related effects of salvinorin A in humans: dissociative, hallucinogenic, and memory effects. Psychopharmacology March 1, 2013
- Psychopharmacology of the hallucinogenic sage Salvia divinorum. Life Sciences December 22, 2005
- Neuropharmacology of the naturally occurring kappa-opioid hallucinogen salvinorin A. Pharmacological Reviews June 1, 2011
- Absorption, Distribution, Metabolism and Excretion Pharmacogenomics of Drugs of Abuse Pharmacogenomics February 1, 2011
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