Natural products from the hallucinogenic sage.
Science progress January 1, 2010 DOI: 10.3184/003685010X12626983776947 (opens in new tab) via PubMed
Summary
AI-generated from the abstractThis review describes the isolation, chemical structures, and biological activity of neoclerodane and other natural products from the Mexican hallucinogenic sage, Salvia divinorum. It covers the plant's secondary metabolites, particularly neoclerodane diterpenes, and their pharmacological properties, including interactions with opioid receptors and other targets relevant to medicinal chemistry and drug discovery. The review consolidates findings on compound isolation, structural elucidation, and bioactivity, highlighting the potential of these natural products for developing new therapeutic agents.
Study at a glance
| Characteristics | Review Peer reviewed |
|---|---|
| Topics | Salvia divinorum |
| Keywords | Natural products Phytochemistry Plant compounds Bioactive compounds Secondary metabolites |
| Citations | 10 |
| Key finding | Salvia divinorum produces neoclerodane diterpenes with diverse biological activities, including opioid receptor modulation, making them promising leads for drug discovery. |
Abstract
The isolation, structures and biological activity of the neoclerodane and other natural products obtained from the Mexican hallucinogenic sage, Salvia divinorum are reviewed.