The journal of pain
January 6, 2026
Mark P Jensen, Marcia A Ciol, Kevin J Gertz et al.
Psychological interventions have reliable but modest effects on chronic pain outcomes, but our understanding of the mechanisms that underlie these effects remains limited. This paper presents the findings from a series of secondary analyses using data from a randomized clinical trial (clinicalTrials.gov, NCT02653664). Three hundred and twenty-eight Veterans of the US Armed Forces with chronic...
The journal of pain
July 21, 2025
Nicholas P. Cherup, Patrick H. Finan
Those living with chronic pain and comorbid functional disabilities are often confronted by a physically and emotionally transformative experience, impacting their identity and ability to derive meaning in life. Despite the use of various pharmacological and non-pharmacological treatments to moderate symptoms, the degree of analgesia and functional recovery are far from optimal. Psychological...
The journal of pain
July 1, 2025
Ingrid Bindicsova, Leanne M Hides, Katherine Brain et al.
1 citation
The purpose of this pilot randomized controlled trial was to examine the feasibility of an internet delivered, self-directed mindfulness-based cognitive therapy (iMBCT) program compared to a delayed treatment (DT) control. This trial employed a 2-group parallel (1:1), design and was pre-registered (ANZCTR Identifier: 12623000833662). Participants were N = 48 adults with chronic pain, randomized...
The journal of pain
May 13, 2025
Zhaochen Zhu, Tim Schouten, Rob Strijkers et al.
1 citation
The objective of the study was to investigate the comparative effectiveness of non-surgical interventions for adults with chronic sciatica. EMBASE, MEDLINE, Cochrane Library, and CINAHL were searched until 7th June 2024 for randomized controlled trials (RCTs) of non-surgical interventions in adults (aged 18 or older) with chronic sciatica (3 months or longer). Primary outcomes were leg pain...
The journal of pain
May 2, 2025
Peter Stilwell, Mael Gagnon-Mailhot, Anne Hudon et al.
8 citations
Suffering is a foundational yet understudied construct within the field of pain. There is general agreement that pain-related suffering involves disruption to one's sense of self. The selfhood literature characterizes two inter-related modes of self-experience. One mode entails in-the-moment experiences that shape one's stream of consciousness; another involves self-reflective thoughts about...
The journal of pain
November 1, 2024
Collin M Calvert, Alex Haley, Emily M Hagel Campbell et al.
Mindfulness-based interventions (MBIs) have been shown to improve chronic pain and associated conditions like depression, anxiety, and sleep disorders. However, there is limited research on how veterans with chronic pain apply mindfulness skills to manage pain in daily life. This cross-sectional study examined the association between applied mindfulness practice, pain, and several pain-related...
The journal of pain
September 1, 2024
Emily P Mills, Rachael L Bosma, Anton Rogachov et al.
5 citations
Neuropathic pain (NP) is a prevalent condition often associated with heightened pain responsiveness suggestive of central sensitization. Neuroimaging biomarkers of treatment outcomes may help develop personalized treatment strategies, but white matter (WM) properties have been underexplored for this purpose. Here we assessed whether WM pathways of the default mode network (DMN: medial...
The journal of pain
July 1, 2024
Patrick H. Finan, Carly Hunt, Michael L. Keaser et al.
18 citations
Positive emotions are a promising target for intervention in chronic pain, but mixed findings across trials to date suggest that existing interventions may not be optimized to efficiently engage the target. The aim of the current pilot mechanistic randomized controlled trial was to test the effects of a positive emotion-enhancing intervention called Savoring Meditation on pain-related neural...
The journal of pain
October 1, 2022
Robert H. Dworkin, Brian T Anderson, Nick Andrews et al.
22 citations
Psychedelic substances have played important roles in diverse cultures, and ingesting various plant preparations to evoke altered states of consciousness has been described throughout recorded history. Accounts of the subjective effects of psychedelics typically focus on spiritual and mystical-type experiences, including feelings of unity, sacredness, and transcendence. Over the past 2 decades,...
The journal of pain
June 1, 2019
Richard Harrison, Fadel Zeidan, George Kitsaras et al.
Mindfulness-based training reduces pain in clinical and experimental settings. Evidence suggests that these beneficial effects are facilitated via an increased focus on the present moment and a reduced emotional enhancement of pain. Most of the existing literature has focused on mindfulness as a learned skill and on the neural mechanisms that underlie the acquisition of this skill. It is...
The journal of pain
August 2010
Sungkun Cho, Elaine M Heiby, Lance M McCracken et al.
Mindfulness involves reducing potential influences from aversive cognitions, sensations, and emotions on behavior. Mindfulness may influence the experience of pain-related anxiety, and thereby enhance other aspects of physical and psychosocial functioning. Thus, the purpose of this study was to investigate a potential mediating role of pain-related anxiety between mindfulness and physical and...
The journal of pain
March 2010
Fadel Zeidan, Nakia S Gordon, Junaid Merchant et al.
This study investigated the effects of brief mindfulness meditation training on ratings of painful electrical stimulation. In Experiment 1, we used a 3-day (20 min/d) mindfulness meditation intervention and measured pain ratings before and after the intervention. Participants' numerical ratings of pain to "low" and "high" electrical stimulation significantly decreased after meditation training....
The journal of pain
September 2008
Natalia E Morone, Cheryl S Lynch, Carol M Greco et al.
To identify the effects of mindfulness meditation on older adults with chronic low back pain (CLBP), we conducted a qualitative study based on grounded theory and used content analysis of diary entries from older adults who had participated in a clinical trial of an 8-week mindfulness meditation program. Participants were 27 adults > or = 65 years of age with CLBP of at least moderate severity...