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Steve O’Brien

3 papers in the library · 196 citations · publishing 2019-2021

Papers

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Debunking the myth of 'Blue Mondays': No evidence of affect drop after taking clinical MDMA.

Journal of Psychopharmacology December 13, 2021 Ben Sessa, Jacob S. Aday, Steve O’Brien et al. 18 citations

BACKGROUND: Incorporating 3,4-methylenedioxymethamphetamine (MDMA) as an adjunct to psychotherapy has shown promise in recent years for treating various mental health conditions, particularly those involving trauma. However, concerns about declines in mood and cognition during the days following dosing, also known as 'Blue Mondays', have been raised as limitations to its clinical use. Although...

DOI: 10.1177/02698811211055809 (opens in new tab) Ecstasy Molly 3 4-methylenedioxymethamphetamine +16

First study of safety and tolerability of 3,4-methylenedioxymethamphetamine-assisted psychotherapy in patients with alcohol use disorder.

Journal of Psychopharmacology February 18, 2021 Ben Sessa, Laurie Higbed, Steve O’Brien et al. 123 citations

Background: 3,4-methylenedioxymethamphetamine (MDMA) therapy has qualities that make it potentially well suited for patients with addictions, but this has never been explored in a research study. We present data from the Bristol Imperial MDMA in Alcoholism (BIMA) study. This is the first MDMA addiction study, an open-label safety and tolerability proof-of-concept study investigating the...

First study of safety and tolerability of 3,4-methylenedioxymethamphetamine (MDMA)-assisted psychotherapy in patients with alcohol use disorder: preliminary data on the first four participants.

BMJ Case Reports July 15, 2019 Ben Sessa, Chloe Sakal, Steve O’Brien et al. 55 citations

We present the preliminary data in an ongoing open-label safety and tolerability proof of concept study exploring the potential role for 3,4-methylenedioxymethamphetamine (MDMA)-assisted psychotherapy in treating patients with alcohol use disorder. At this stage, seven participants have completed the full 8-week MDMA-assisted psychotherapy course, including two therapy sessions each with MDMA....