Objective: To describe the neuroanatomical correlations of an isolated lesion in the anterior thalamus using functional imaging in a 40-year-old man with multiple sclerosis. Design: Case report with 10 cognitively normal controls. Setting: Mayo Clinic, Rochester, Minnesota. Patient: A 40-year-old man with a 2-week course of acute-onset amnesia, abulia, poor concentration, hypersomnolence, and...
Know Thyself or Journal of Empirical Psychology (Gnothi Sauton oder Magazin zur Erfahrungsseelenkunde), 1783-1793, was the first of its kind--concentrating on nervous and mental disturbances and marking the beginning of periodical neuropsychiatric publications. The editor, Karl Philipp Moritz, and the contributors, many of them lay people, were particularly interested in disturbances of...
We report the cases of 10 patients with seizures and autoscopic phenomena, which include seeing one's double and out-of-body experiences, and review 33 additional cases of autoscopic seizures from the literature. Autoscopic phenomena may be symptoms of simple partial, complex partial, or generalized tonoclonic seizures. Autoscopic seizures may be more common than is recognized; we found a 6.3%...
The paradoxical aspects of dreams have always been interpreted according to prevalent ways of thinking. Dreams as premonitions of disease have been reported since the classical era, and hypnagogic hallucinations, so named by Alfred Maury and viewed as "psychosensory hallucinations" by Baillarger in the 1840s (extending the Kantian definition of the madman as a "waking dreamer"), have been...
Rare case reports have indicated that brain lesions may cause a loss of dream recall. We investigated reports of dream recallers with acute unilateral brain lesions who did not have clinical agnosia and examined 53 patients with such focal lesions clinically and radiologically. Patients with posterior lesions showed a frequent loss of dream recall while those with anterior lesions rarely did...
Introduction The significance to behavior of biologically active amines normally present in the mammalian brain has been receiving increased attention by workers in diversified fields in recent years. This trend has been accelerated by the recognition that a number of potent psychotherapeutic agents seem to assert their beneficial effects by influencing these amines in various ways. For...