A simplified method of studying the surfacing reaction of goldfish to hallucinogens is described. Goldfish weighing up to three grams are injected intracranially. Employing this method, d-lysergic acid diethylamide (LSD-25), d-2-acetyl lysergic acid diethylamide (ALD-52), 1-methyl d-lysergic acid butano-lamide (UML-491), and 5-methoxy dimethyl tryptamine (5-MEO-DMT) were found to be as...
This paper is a continuation of our experiments with LSD-25 and similar compounds that have been carried out for the last thirteen years.1 It employs the same technique described previously2 to compare these drugs on non-psychotic test subjects under suitable conditions. The conditions of the experiment are most important because under certain circumstances the experimental milieu produces so...