Mescaline produced an inhibitory state accompanied by a schizokenesis or dissociation of systems. This disharmony was also manifested in that the CS appeared to act in the same manner as the US. On this basis a neurodynamic theory of the mechanism of mescaline's actions is postulated: that under mescaline intoxication and in some mental illnesses, a dissociation of the second and first...
Lysergic acid diethylamide (LSD-25 Sandoz) given orally in single doses as low as 20 micrograms produces depersonalization, derealization, and increased imagery in "normal" individuals. Larger doses are required to produce the same effect in psychotic patients. Of 15 patients with depressive reactions, 3 recovered and 4 improved after one month's treatment with daily oral doses of 20-100...
The effects of mescaline and lysergic acid were studied in schizophrenic patients. It was found that physiological changes were produced in these patients and that their mental symptomatology was markedly aggravated. The observations made with the above-mentioned drugs on normal individuals were compared with those seen in schizophrenic patients. Mescaline and lysergic acid are drugs that...
This paper discusses theoretical points of drug-induced abnormal mental states. The reaction of 3 different drugs, sodium amytal, pervitin, and mescaline, on the same individual is described and the differences noted. The relationship of personality type to drug reaction is evaluated and the normalizing and disorganizing effect of certain drugs on mental patients discussed.
Intravenous injection of synthetic mescaline was used in a group of schizophrenic patients and on "normal" voluntary controls. The changes produced by mescaline in "normals" were described. In addition, the observations were made that mescaline is able to underscore in patients suffering from schizophrenia their schizophrenic symptoms or able to precipitate schizophrenic psychoses in persons...
Mescaline produces altered visual experiences of several types, whose vividness and degree of distortion is proportionate to the size of the dose. There are no sharp boundaries dividing abnormal sensibility, illusions, and hallucinations. Subjects who gave fewer responses of the type "I see it" when asked to imagine situations were more likely to hallucinate than other patients. Visual...
The records of three groups of children—normal, preschool children; children with behavior and neurotic problems; and finally, psychotic children—were analyzed with a view of gaining information about and insight into hallucinatory and delusional phenomena in children. The large majority of the children belonged in the normal and superior range of intellectual functioning. No evidence of true...